Indication

Allergic fungal rhinosinusitis

Allergic fungal rhinosinusitis is a distinct, noninvasive clinical subtype of chronic rhinosinusitis with nasal polyps driven by an intense type 2 hypersensitivity response to colonizing environmental fungi. Read more about Allergic fungal rhinosinusitis

3 drugs 1 manufacturers

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Drugs that treat it

Common Allergic fungal rhinosinusitis therapies.

Showing 1–3 of 3 drugs

DUPIXENT (dupilumab)

ECZEMA AGENTS SYSTEMIC INTERLEUKIN-4 (IL-4RA)ANTAG.MCAB·ATOPIC DERMATITIS·+10
Sanofi-Aventis U.S.

DUPIXENT PEN (dupilumab)

ECZEMA AGENTS SYSTEMIC INTERLEUKIN-4 (IL-4RA)ANTAG.MCAB·ATOPIC DERMATITIS·+10
Sanofi-Aventis U.S.
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About Allergic fungal rhinosinusitis.

Allergic fungal rhinosinusitis is a distinct, noninvasive clinical subtype of chronic rhinosinusitis with nasal polyps driven by an intense type 2 hypersensitivity response to colonizing environmental fungi.

It primarily affects the sinonasal tract of immunocompetent, typically atopic adolescents and young adults.

Pathophysiologically and clinically, it is characterized by extensive bilateral or unilateral nasal polyposis, immunoglobulin E-mediated hypersensitivity, and the accumulation of thick, eosinophil-rich "allergic mucin" containing noninvasive fungal hyphae and Charcot-Leyden crystals.

Continued accumulation of this dense mucin frequently produces an expansile mass effect that can erode adjacent bony sinus walls and extend toward the orbit or skull base.

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