Indication

Allergic rhinitis due to ragweed pollen

Allergic rhinitis due to ragweed pollen is a seasonal, immunoglobulin E (IgE)–mediated inflammatory disorder of the upper respiratory tract triggered by airborne pollen from the *Ambrosia* species. Read more about Allergic rhinitis due to ragweed pollen

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About Allergic rhinitis due to ragweed pollen.

Allergic rhinitis due to ragweed pollen is a seasonal, immunoglobulin E (IgE)–mediated inflammatory disorder of the upper respiratory tract triggered by airborne pollen from the *Ambrosia* species.

Primarily affecting sensitized children and adults during the late summer and autumn pollination seasons, it involves the nasal mucosa and frequently extends to the conjunctiva.

Pathophysiologically, the inhalation of ragweed allergens induces cross-linking of specific IgE on mucosal mast cells and basophils, prompting the release of histamine, leukotrienes, and inflammatory cytokines.

This acute- and late-phase inflammation classically produces paroxysmal sneezing, nasal congestion, anterior rhinorrhea, and nasopharyngeal or ocular pruritus.

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