Indication

Anxiety associated with menopause

Anxiety associated with menopause refers to the onset or exacerbation of affective and somatic anxiety symptoms occurring during the climacteric transition, predominantly affecting perimenopausal and postmenopausal women. Read more about Anxiety associated with menopause

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About Anxiety associated with menopause.

Anxiety associated with menopause refers to the onset or exacerbation of affective and somatic anxiety symptoms occurring during the climacteric transition, predominantly affecting perimenopausal and postmenopausal women.

This condition involves both the central nervous and endocrine systems, driven by neuroendocrine dysregulation linked to fluctuating and declining ovarian steroid hormones, particularly estradiol and progesterone.

These hormonal shifts alter hypothalamic-pituitary-adrenal axis reactivity and disrupt key neurotransmitter networks, including gamma-aminobutyric acid and serotonergic pathways.

Clinically, it presents as persistent nervousness, excessive worry, cognitive disturbances, and episodic panic, frequently compounded by somatic manifestations such as sleep fragmentation, palpitations, and concurrent vasomotor symptoms.

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