Indication

Blepharospasm

Blepharospasm is a focal cranial dystonia characterized by involuntary, repetitive, or sustained contractions of the orbicularis oculi and associated periorbital muscles. Read more about Blepharospasm

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About Blepharospasm.

Blepharospasm is a focal cranial dystonia characterized by involuntary, repetitive, or sustained contractions of the orbicularis oculi and associated periorbital muscles.

This neurological movement disorder predominantly affects middle-aged and older adults, with a notable female predominance.

Pathophysiologically, it involves impaired sensorimotor integration and loss of central inhibition within basal ganglia-thalamocortical and cerebellar circuits, often manifesting as an idiopathic condition known as benign essential blepharospasm or occurring secondary to local ocular irritation or central neurodegenerative pathology.

Clinically, it features progressive bilateral eyelid fluttering, excessive blinking, and forceful involuntary eye closure that can be exacerbated by stress or bright light, potentially culminating in functional blindness despite intact ocular visual pathways.

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