CD30-positive mycosis fungoides

CD30-positive mycosis fungoides is a subtype of mycosis fungoides—the most common form of cutaneous T-cell lymphoma—distinguished by the immunohistochemical expression of the cell-surface marker CD30 on malignant T lymphocytes It primarily targets the skin in adult populations and may manifest across disease stages as persistent patches, indurated plaques, or cutaneous tumors, often arising during large-cell transformation or in advanced progression Pathophysiologically, epidermotropic and derma...

CD30-positive mycosis fungoides is a subtype of mycosis fungoides—the most common form of cutaneous T-cell lymphoma—distinguished by the immunohistochemical expression of the cell-surface marker CD30 on malignant T lymphocytes Pathophysiologically, epidermotropic and dermal malignant helper T cells upregulate this tumor necrosis factor receptor superfamily member, providing a defined biomarker that differentiates it from typical CD30-negative presentations and indicates potential susceptibility ...

It primarily targets the skin in adult populations and may manifest across disease stages as persistent patches, indurated plaques, or cutaneous tumors, often arising during large-cell transformation or in advanced progression

It primarily targets the skin in adult populations and may manifest across disease stages as persistent patches, indurated plaques, or cutaneous tumors, often arising during large-cell transformation or in advanced progression