Indication
Chronic graft-versus-host disease
Chronic graft-versus-host disease is a serious, multi-organ alloimmune and autoimmune-like complication that occurs following allogeneic hematopoietic cell transplantation. Read more about Chronic graft-versus-host disease
6 drugs 3 manufacturers
Drugs that treat it
Common Chronic graft-versus-host disease therapies.
IMBRUVICA (ibrutinib)
IMBRUVICA (ibrutinib)
REZUROCK (belumosudil mesylate)
NIKTIMVO (axatilimab-csfr)
JAKAFI XR (ruxolitinib phosphate)
News & literature
Coming soonRelated codes
Coming soonRelated conditions & guidelines
Coming soonChronic graft-versus-host disease is a serious, multi-organ alloimmune and autoimmune-like complication that occurs following allogeneic hematopoietic cell transplantation.
The disease arises when donor-derived immunocompetent T and B cells recognize recipient tissues as foreign, initiating dysregulated immune responses, persistent inflammation, and progressive tissue fibrosis.
It frequently involves the skin, oral mucosa, eyes, liver, gastrointestinal tract, musculoskeletal system, and lungs, leading to clinical manifestations such as sclerotic or lichenoid changes, keratoconjunctivitis sicca, joint contractures, and bronchiolitis obliterans.
Chronic graft-versus-host disease remains a leading cause of late non-relapse morbidity and mortality in post-transplant populations.
- nih.gov
Chronic graft-versus-host disease is a serious, multi-organ alloimmune and autoimmune-like complication that occurs following allogeneic hematopoietic cell transplantation
- nih.gov
Chronic graft-versus-host disease is a serious, multi-organ alloimmune and autoimmune-like complication that occurs following allogeneic hematopoietic cell transplantation The disease arises when donor-derived immunocompetent T and B cells recognize recipient tissues as foreign, initiating dysregulated immune responses, persistent inflammation, and progressive tissue fibrosis Chronic graft-versus-host disease remains a leading cause of late non-relapse morbidity and mortality in post-transplant ...
- nih.gov
The disease arises when donor-derived immunocompetent T and B cells recognize recipient tissues as foreign, initiating dysregulated immune responses, persistent inflammation, and progressive tissue fibrosis
- cancer.gov
The disease arises when donor-derived immunocompetent T and B cells recognize recipient tissues as foreign, initiating dysregulated immune responses, persistent inflammation, and progressive tissue fibrosis It frequently involves the skin, oral mucosa, eyes, liver, gastrointestinal tract, musculoskeletal system, and lungs, leading to clinical manifestations such as sclerotic or lichenoid changes, keratoconjunctivitis sicca, joint contractures, and bronchiolitis obliterans
- cancer.gov
It frequently involves the skin, oral mucosa, eyes, liver, gastrointestinal tract, musculoskeletal system, and lungs, leading to clinical manifestations such as sclerotic or lichenoid changes, keratoconjunctivitis sicca, joint contractures, and bronchiolitis obliterans
- dana-farber.org
It frequently involves the skin, oral mucosa, eyes, liver, gastrointestinal tract, musculoskeletal system, and lungs, leading to clinical manifestations such as sclerotic or lichenoid changes, keratoconjunctivitis sicca, joint contractures, and bronchiolitis obliterans
- ashpublications.org
Chronic graft-versus-host disease remains a leading cause of late non-relapse morbidity and mortality in post-transplant populations
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