Corneal erosion

Corneal erosion is an ocular condition characterized by the detachment or loss of the outermost corneal epithelial layer from the underlying epithelial basement membrane and Bowman's layer It most commonly affects individuals with a history of mechanical corneal trauma or those predisposed by underlying anterior corneal dystrophies, such as epithelial basement membrane dystrophy Pathophysiologically, defective adhesion complexes—including impaired hemidesmosomes and basement membrane abnormaliti...

Corneal erosion is an ocular condition characterized by the detachment or loss of the outermost corneal epithelial layer from the underlying epithelial basement membrane and Bowman's layer Pathophysiologically, defective adhesion complexes—including impaired hemidesmosomes and basement membrane abnormalities—cause the fragile epithelium to slough off, frequently triggered by the shearing mechanical force of eyelid movement upon awakening

It most commonly affects individuals with a history of mechanical corneal trauma or those predisposed by underlying anterior corneal dystrophies, such as epithelial basement membrane dystrophy

Clinically, it manifests as acute, severe eye pain, foreign-body sensation, photophobia, excessive lacrimation, and focal epithelial defects visible on slit-lamp examination with fluorescein staining

Clinically, it manifests as acute, severe eye pain, foreign-body sensation, photophobia, excessive lacrimation, and focal epithelial defects visible on slit-lamp examination with fluorescein staining