Indication

Dengue vaccination

Dengue vaccination is a preventative immunization indicated to reduce the risk of dengue disease, hospitalization, and severe secondary illness caused by dengue virus serotypes 1, 2, 3, and 4. Read more about Dengue vaccination

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About Dengue vaccination.

Dengue vaccination is a preventative immunization indicated to reduce the risk of dengue disease, hospitalization, and severe secondary illness caused by dengue virus serotypes 1, 2, 3, and 4.

Transmitted primarily by *Aedes* mosquitoes, dengue is an acute systemic flavivirus infection that clinically presents with high fever, severe retro-orbital headache, arthralgia, myalgia, and rash.

In susceptible individuals—particularly upon secondary heterotypic infection due to antibody-dependent enhancement—the condition can progress to severe plasma leakage, profound thrombocytopenia, severe hemorrhage, and dengue shock syndrome.

Regulatory and public health indications typically target pediatric populations in dengue-endemic areas who have laboratory-confirmed evidence of prior dengue infection, as pre-existing seropositivity is essential to avoid priming seronegative individuals for subsequent severe disease.

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