Indication

Diffuse astrocytoma

Diffuse astrocytoma is an infiltrative, slow-growing primary central nervous system neoplasm arising from star-shaped glial cells known as astrocytes. Read more about Diffuse astrocytoma

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About Diffuse astrocytoma.

Diffuse astrocytoma is an infiltrative, slow-growing primary central nervous system neoplasm arising from star-shaped glial cells known as astrocytes.

Most commonly diagnosed in young to middle-aged adults, it typically develops in the cerebral hemispheres of the brain but can affect other neuroaxial sites.

Pathophysiologically, it is historically classified as a low-grade (World Health Organization grade 2) glioma characterized by cellular atypia and ill-defined margins that invade adjacent neural parenchyma without significant necrosis or microvascular proliferation.

Patients frequently present with new-onset seizures, persistent headaches, or progressive focal neurological deficits, and the neoplasm carries an inherent tendency over time to recur or progress to higher-grade malignancies.

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