Indication

Eosinophilic esophagitis

Eosinophilic esophagitis is a chronic, immune- and antigen-mediated inflammatory disorder affecting the gastrointestinal tract, specifically the esophagus. Read more about Eosinophilic esophagitis

4 drugs 2 manufacturers

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Drugs that treat it

Common Eosinophilic esophagitis therapies.

Showing 1–4 of 4 drugs

DUPIXENT (dupilumab)

ECZEMA AGENTS SYSTEMIC INTERLEUKIN-4 (IL-4RA)ANTAG.MCAB·ATOPIC DERMATITIS·+10
Sanofi-Aventis U.S.

DUPIXENT PEN (dupilumab)

ECZEMA AGENTS SYSTEMIC INTERLEUKIN-4 (IL-4RA)ANTAG.MCAB·ATOPIC DERMATITIS·+10
Sanofi-Aventis U.S.
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About Eosinophilic esophagitis.

Eosinophilic esophagitis is a chronic, immune- and antigen-mediated inflammatory disorder affecting the gastrointestinal tract, specifically the esophagus.

It can occur in both pediatric and adult populations, frequently in individuals with concurrent atopic conditions.

Pathophysiologically, localized type 2 helper T-cell inflammation triggered by food or aeroallergens drives epithelial barrier disruption and dense eosinophilic infiltration of the esophageal mucosa.

Over time, persistent inflammation leads to tissue remodeling and progressive esophageal dysfunction, commonly presenting as dysphagia, chest pain, and food impaction in adults, or feeding refusal, vomiting, and failure to thrive in young children.

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