Indication

Fluid retention associated with menses

Fluid retention associated with menses is a cyclical clinical state characterized by temporary extracellular water and sodium accumulation occurring during the late luteal phase and early onset of menstruation. Read more about Fluid retention associated with menses

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About Fluid retention associated with menses.

Fluid retention associated with menses is a cyclical clinical state characterized by temporary extracellular water and sodium accumulation occurring during the late luteal phase and early onset of menstruation.

Affecting ovulatory and menstruating females across their reproductive lifespan, it primarily impacts systemic fluid regulation, the vascular endothelium, and peripheral interstitial tissues.

It is pathophysiologically driven by shifting ovarian sex hormone levels, primarily fluctuations in estrogen and progesterone that influence the renin-angiotensin-aldosterone axis and capillary permeability.

Clinically, it manifests as transient abdominal bloating, peripheral edema of the extremities, breast engorgement or tenderness, and modest, self-limiting weight gain that typically resolves following the establishment of menstrual flow.

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