Fungal endocarditis

Fungal endocarditis is a severe, life-threatening form of infective endocarditis caused by fungal colonization of the cardiac endocardium, heart valves, or implanted cardiovascular devices

Fungal endocarditis is a severe, life-threatening form of infective endocarditis caused by fungal colonization of the cardiac endocardium, heart valves, or implanted cardiovascular devices It predominantly affects the cardiovascular system, occurring most frequently in vulnerable populations such as immunocompromised individuals, patients with prosthetic valves or indwelling central lines, recipients of broad-spectrum antimicrobials, and people who inject drugs Pathophysiologically, opportunisti...

It predominantly affects the cardiovascular system, occurring most frequently in vulnerable populations such as immunocompromised individuals, patients with prosthetic valves or indwelling central lines, recipients of broad-spectrum antimicrobials, and people who inject drugs

Pathophysiologically, opportunistic yeasts or molds—most commonly *Candida* and *Aspergillus* species—adhere to damaged endocardium or foreign material and generate bulky, friable vegetations These massive vegetations frequently lead to valve destruction, severe cardiac failure, and high rates of major arterial embolic events and metastatic infection

These massive vegetations frequently lead to valve destruction, severe cardiac failure, and high rates of major arterial embolic events and metastatic infection