Fungal meningitis

Fungal meningitis is a rare, life-threatening infection marked by inflammation of the protective membranes surrounding the brain and spinal cord It primarily impacts immunocompromised populations, such as individuals with advanced HIV disease or those receiving immunosuppressive therapies, though it can occasionally affect immunocompetent hosts or arise from direct iatrogenic inoculation into the central nervous system Pathophysiologically, it typically develops when inhaled fungal spores—most c...

Fungal meningitis is a rare, life-threatening infection marked by inflammation of the protective membranes surrounding the brain and spinal cord

It primarily impacts immunocompromised populations, such as individuals with advanced HIV disease or those receiving immunosuppressive therapies, though it can occasionally affect immunocompetent hosts or arise from direct iatrogenic inoculation into the central nervous system

It primarily impacts immunocompromised populations, such as individuals with advanced HIV disease or those receiving immunosuppressive therapies, though it can occasionally affect immunocompetent hosts or arise from direct iatrogenic inoculation into the central nervous system Pathophysiologically, it typically develops when inhaled fungal spores—most commonly *Cryptococcus*, *Coccidioides*, or *Histoplasma* species—disseminate hematogenously across the blood-brain barrier

Pathophysiologically, it typically develops when inhaled fungal spores—most commonly *Cryptococcus*, *Coccidioides*, or *Histoplasma* species—disseminate hematogenously across the blood-brain barrier The condition characteristically presents with an insidious or subacute onset of persistent headache, fever, neck stiffness, altered mental status, and complications related to elevated intracranial pressure