Indication

Growth failure secondary to chronic renal failure

Growth failure secondary to chronic renal failure is a pediatric endocrine and musculoskeletal complication characterized by a significant deceleration in linear height velocity and progressive short stature resulting from long-standing renal impairment. Read more about Growth failure secondary to chronic renal failure

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ZOMACTON (somatropin)

GROWTH HORMONE MODULATORS·PITUITARY DWARFISM·+4

FERRING PH INC

NUTROPIN AQ NUSPIN (somatropin)

GROWTH HORMONE MODULATORS·PITUITARY DWARFISM·+4

GENENTECH

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About Growth failure secondary to chronic renal failure.

The condition typically presents in infants, children, and adolescents with moderate-to-severe chronic kidney disease or end-stage renal disease.

Pathophysiologically, the impairment is multifactorial, driven primarily by functional resistance to growth hormone and reduced insulin-like growth factor-1 bioactivity despite normal or elevated circulating growth hormone levels.

This hormonal dysregulation is further exacerbated by chronic metabolic acidosis, protein-calorie malnutrition, anemia, systemic inflammation, and mineral and bone disorders associated with secondary hyperparathyroidism.

nih.gov
Growth failure secondary to chronic renal failure is a pediatric endocrine and musculoskeletal complication characterized by a significant deceleration in linear height velocity and progressive short stature resulting from long-standing renal impairment
nih.gov
Growth failure secondary to chronic renal failure is a pediatric endocrine and musculoskeletal complication characterized by a significant deceleration in linear height velocity and progressive short stature resulting from long-standing renal impairment This hormonal dysregulation is further exacerbated by chronic metabolic acidosis, protein-calorie malnutrition, anemia, systemic inflammation, and mineral and bone disorders associated with secondary hyperparathyroidism
karger.com
Growth failure secondary to chronic renal failure is a pediatric endocrine and musculoskeletal complication characterized by a significant deceleration in linear height velocity and progressive short stature resulting from long-standing renal impairment This hormonal dysregulation is further exacerbated by chronic metabolic acidosis, protein-calorie malnutrition, anemia, systemic inflammation, and mineral and bone disorders associated with secondary hyperparathyroidism
nih.gov
The condition typically presents in infants, children, and adolescents with moderate-to-severe chronic kidney disease or end-stage renal disease
cambridge.org
The condition typically presents in infants, children, and adolescents with moderate-to-severe chronic kidney disease or end-stage renal disease
nih.gov
Pathophysiologically, the impairment is multifactorial, driven primarily by functional resistance to growth hormone and reduced insulin-like growth factor-1 bioactivity despite normal or elevated circulating growth hormone levels
nih.gov
Pathophysiologically, the impairment is multifactorial, driven primarily by functional resistance to growth hormone and reduced insulin-like growth factor-1 bioactivity despite normal or elevated circulating growth hormone levels
nih.gov
Pathophysiologically, the impairment is multifactorial, driven primarily by functional resistance to growth hormone and reduced insulin-like growth factor-1 bioactivity despite normal or elevated circulating growth hormone levels
nih.gov
This hormonal dysregulation is further exacerbated by chronic metabolic acidosis, protein-calorie malnutrition, anemia, systemic inflammation, and mineral and bone disorders associated with secondary hyperparathyroidism

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