Indication

Heart failure with mid range ejection fraction

Heart failure with mid range ejection fraction is a cardiovascular syndrome characterized by typical heart failure symptoms—such as dyspnea, fatigue, and fluid retention—in patients with a left ventricular ejection fraction intermediate between reduced and preserved parameters, specifically 40% to 49%. Read more about Heart failure with mid range ejection fraction

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About Heart failure with mid range ejection fraction.

Heart failure with mid range ejection fraction is a cardiovascular syndrome characterized by typical heart failure symptoms—such as dyspnea, fatigue, and fluid retention—in patients with a left ventricular ejection fraction intermediate between reduced and preserved parameters, specifically 40% to 49%.

This condition reflects an intermediate pathophysiologic state involving mild systolic dysfunction often combined with diastolic impairment and elevated intracardiac filling pressures.

Patients typically present with elevated natriuretic peptides, underlying structural heart disease such as left ventricular hypertrophy or left atrial enlargement, and a high prevalence of ischemic coronary disease and cardiometabolic comorbidities.

Many clinical guidelines also classify this distinct clinical phenotype as heart failure with mildly reduced ejection fraction.

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