Indication

Hypocalcemia associated with hypoparathyroidism

Hypocalcemia associated with hypoparathyroidism is a metabolic state characterized by subnormal circulating calcium concentrations resulting from absent or deficient secretion of parathyroid hormone (PTH). Read more about Hypocalcemia associated with hypoparathyroidism

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About Hypocalcemia associated with hypoparathyroidism.

Hypocalcemia associated with hypoparathyroidism is a metabolic state characterized by subnormal circulating calcium concentrations resulting from absent or deficient secretion of parathyroid hormone (PTH).

This endocrine disorder impairs normal bone resorption, reduces renal calcium reabsorption, and decreases renal synthesis of 1,25-dihydroxyvitamin D, frequently leading to concurrent hyperphosphatemia.

Primarily affecting the neuromuscular and cardiovascular systems, this electrolyte derangement increases neuromuscular excitability, manifesting clinically as perioral paresthesias, muscle cramping, carpopedal spasm, tetany, seizures, or cardiac dysrhythmias.

It most commonly occurs in adults following anterior neck surgery, such as thyroidectomy, but may also stem from autoimmune destruction or rare genetic disorders.

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