Iodine deficiency

Iodine deficiency is a nutritional disorder caused by inadequate intake or bioavailability of the essential trace element iodine, which impairs normal thyroid hormone synthesis It primarily affects the endocrine and central nervous systems across all age groups, with pregnant individuals, fetuses, infants, and young children being the most clinically vulnerable populations Severe or prolonged deficiency can progress to overt hypothyroidism and precipitate irreversible neurodevelopmental complica...

Iodine deficiency is a nutritional disorder caused by inadequate intake or bioavailability of the essential trace element iodine, which impairs normal thyroid hormone synthesis It primarily affects the endocrine and central nervous systems across all age groups, with pregnant individuals, fetuses, infants, and young children being the most clinically vulnerable populations Pathophysiologically, depleted iodine stores limit the production of thyroxine (T4) and triiodothyronine (T3), prompting a c...

Iodine deficiency is a nutritional disorder caused by inadequate intake or bioavailability of the essential trace element iodine, which impairs normal thyroid hormone synthesis Pathophysiologically, depleted iodine stores limit the production of thyroxine (T4) and triiodothyronine (T3), prompting a compensatory rise in thyroid-stimulating hormone (TSH) secretion that triggers thyroid follicular hypertrophy and goiter formation Severe or prolonged deficiency can progress to overt hypothyroidism a...

It primarily affects the endocrine and central nervous systems across all age groups, with pregnant individuals, fetuses, infants, and young children being the most clinically vulnerable populations

Pathophysiologically, depleted iodine stores limit the production of thyroxine (T4) and triiodothyronine (T3), prompting a compensatory rise in thyroid-stimulating hormone (TSH) secretion that triggers thyroid follicular hypertrophy and goiter formation

Severe or prolonged deficiency can progress to overt hypothyroidism and precipitate irreversible neurodevelopmental complications, including endemic cretinism, congenital intellectual disability, and impaired somatic growth