YONDELIS (trabectedin)
ANTINEOPLASTIC - TOPOISOMERASE I INHIBITORS·LEIOMYOSARCOMA·+1
JANSSEN PRODUCT
Indication
Leiomyosarcoma
Leiomyosarcoma is an aggressive, rare soft tissue sarcoma arising from smooth muscle cells or their mesenchymal precursors, accounting for approximately 10% to 20% of all soft tissue sarcomas. Read more about Leiomyosarcoma
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Drugs that treat it
Common Leiomyosarcoma therapies.
EVDI (trabectedin)
ANTINEOPLASTIC - TOPOISOMERASE I INHIBITORS·LEIOMYOSARCOMA·+1
APOTEX CORP
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News & literature
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Coming soonRelated conditions & guidelines
Coming soonLeiomyosarcoma is an aggressive, rare soft tissue sarcoma arising from smooth muscle cells or their mesenchymal precursors, accounting for approximately 10% to 20% of all soft tissue sarcomas.
It occurs predominantly in adults, with the most frequent anatomical sites being the uterus, retroperitoneum, intra-abdominal viscera, large blood vessels, and somatic soft tissues of the extremities.
Histopathologically, the malignancy is characterized by intersecting fascicles of spindled cells exhibiting marked nuclear atypia, pleomorphism, brisk mitotic activity, and coagulative tumor cell necrosis.
Because of its invasive biology, it frequently manifests as a rapidly enlarging mass and carries a high propensity for hematogenous dissemination, most commonly metastasizing to the lungs and liver.
- cancer.gov
Leiomyosarcoma is an aggressive, rare soft tissue sarcoma arising from smooth muscle cells or their mesenchymal precursors, accounting for approximately 10% to 20% of all soft tissue sarcomas
- nih.gov
Leiomyosarcoma is an aggressive, rare soft tissue sarcoma arising from smooth muscle cells or their mesenchymal precursors, accounting for approximately 10% to 20% of all soft tissue sarcomas It occurs predominantly in adults, with the most frequent anatomical sites being the uterus, retroperitoneum, intra-abdominal viscera, large blood vessels, and somatic soft tissues of the extremities
- nih.gov
It occurs predominantly in adults, with the most frequent anatomical sites being the uterus, retroperitoneum, intra-abdominal viscera, large blood vessels, and somatic soft tissues of the extremities
- nih.gov
Because of its invasive biology, it frequently manifests as a rapidly enlarging mass and carries a high propensity for hematogenous dissemination, most commonly metastasizing to the lungs and liver
- stonybrookmedicine.edu
Because of its invasive biology, it frequently manifests as a rapidly enlarging mass and carries a high propensity for hematogenous dissemination, most commonly metastasizing to the lungs and liver
- nih.gov
Because of its invasive biology, it frequently manifests as a rapidly enlarging mass and carries a high propensity for hematogenous dissemination, most commonly metastasizing to the lungs and liver
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