Indication

Low-grade upper tract urothelial cancer

**Low-grade upper tract urothelial cancer** (UTUC) is a rare subtype of urothelial malignancy affecting the epithelial lining of the upper urinary tract, specifically the renal pelvis and ureters. Read more about Low-grade upper tract urothelial cancer

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About Low-grade upper tract urothelial cancer.

**Low-grade upper tract urothelial cancer** (UTUC) is a rare subtype of urothelial malignancy affecting the epithelial lining of the upper urinary tract, specifically the renal pelvis and ureters.

Histologically classified as low grade, these lesions are typically well-differentiated, non-invasive papillary neoplasms with minimal cellular atypia and low metastatic potential.

Clinically, they most commonly present with macroscopic or microscopic hematuria and flank pain or hydronephrosis secondary to luminal obstruction.

Although cancer-specific mortality is low, the condition is characterized by a pronounced tendency toward frequent local recurrence within the urinary tract and significant challenges in complete endoscopic eradication.

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