Indication

Lower limb spasticity

Lower limb spasticity is a neuromuscular condition characterized by a velocity-dependent increase in tonic stretch reflexes and muscle tone affecting the hip, thigh, leg, ankle, or foot. Read more about Lower limb spasticity

6 drugs 5 manufacturers

Advertisement

Drugs that treat it

Common Lower limb spasticity therapies.

Showing 1–6 of 6 drugs

Filter & compare in the drug finder →Opens the drug finder with Lower limb spasticity preselected.

News & literature

Coming soon

Related codes

Coming soon
Coming soon

About Lower limb spasticity.

Lower limb spasticity is a neuromuscular condition characterized by a velocity-dependent increase in tonic stretch reflexes and muscle tone affecting the hip, thigh, leg, ankle, or foot.

It develops as a component of upper motor neuron syndrome following central nervous system injury—such as from stroke, spinal cord injury, traumatic brain injury, multiple sclerosis, or cerebral palsy—which disrupts descending inhibitory supraspinal control and produces hyperexcitable spinal stretch reflex arcs.

Clinically, affected individuals present with exaggerated tendon jerks, clonus, painful spasms, and abnormal lower-extremity posture, commonly involving excessive knee extension, hip adduction, or ankle plantarflexion (equinovarus deformity).

Without adequate intervention, this hypertonia can significantly impair mobility, gait, and transfers, often predisposing patients to secondary soft-tissue contractures and musculoskeletal deformities.

Personalize your experience

Follow Lower limb spasticity and get updates as they land.

Create a free account

Follow an indication and get alerts when its drugs, labels, or guidelines change

Save any drug on this page to your favorites, synced across devices

AI-curated peer-reviewed research, summarized for your specialty

A morning digest of indication-relevant updates, when you want it