Indication

Mpox vaccination

Mpox vaccination is an active immunization procedure indicated for the pre-exposure prophylaxis or post-exposure prevention of disease caused by the mpox virus, an Orthopoxvirus. Read more about Mpox vaccination

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About Mpox vaccination.

Mpox vaccination is an active immunization procedure indicated for the pre-exposure prophylaxis or post-exposure prevention of disease caused by the mpox virus, an Orthopoxvirus.

It is indicated for individuals at elevated risk of infection, including persons with known or suspected recent exposure, populations with behavioral or sexual epidemiological risk factors during outbreaks, and personnel with occupational exposure to orthopoxviruses.

The target condition involves systemic infection following mucosal or cutaneous viral entry, characterized clinically by a prodromal febrile syndrome, prominent lymphadenopathy, and progressive, painful mucocutaneous lesions evolving from maculopapular eruptions to vesicles, pseudo-pustules, and crusts.

Prophylaxis aims to elicit neutralizing cross-protective humoral and cell-mediated immune responses to prevent viral replication, severe cutaneous or visceral involvement, and secondary clinical complications.

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