Indication

Myocardial ischemia

Myocardial ischemia is a cardiovascular condition defined by a critical imbalance between coronary blood flow and myocardial metabolic demand, leading to inadequate perfusion and oxygenation of the heart muscle. Read more about Myocardial ischemia

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About Myocardial ischemia.

Myocardial ischemia is a cardiovascular condition defined by a critical imbalance between coronary blood flow and myocardial metabolic demand, leading to inadequate perfusion and oxygenation of the heart muscle.

It predominantly affects adults with obstructive atherosclerotic coronary artery disease, microvascular dysfunction, or coronary vasospasm.

Pathophysiologically, cellular hypoxia triggers a shift to anaerobic glycolysis, impaired contractile function, and tissue acidosis, which can progress to cardiomyocyte necrosis if perfusion is not promptly restored.

Clinically, it manifests along a continuum ranging from silent ischemia to exertional angina pectoris, dyspnea, and acute coronary syndromes with ischemic electrocardiographic abnormalities.

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