Indication

Nonalcoholic steatohepatitis

Nonalcoholic steatohepatitis is an advanced, progressive subtype of nonalcoholic fatty liver disease affecting the hepatic system, predominantly occurring in individuals with obesity, insulin resistance, type 2 diabetes, or metabolic syndrome in the absence of significant alcohol consumption. Read more about Nonalcoholic steatohepatitis

3 drugs 2 manufacturers

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Drugs that treat it

Common Nonalcoholic steatohepatitis therapies.

Showing 1–3 of 3 drugs

WEGOVY (semaglutide)

DIET AIDS·WEIGHT LOSS MANAGEMENT FOR OBESE PATIENT (BODY MASS INDEX 30 OR GREATER)·+3
NOVO NORDISK

WEGOVY (semaglutide)

DIET AIDS·WEIGHT LOSS MANAGEMENT FOR OBESE PATIENT (BODY MASS INDEX 30 OR GREATER)·+3
A-S MEDICATION

WEGOVY HD (semaglutide)

DIET AIDS·WEIGHT LOSS MANAGEMENT FOR OBESE PATIENT (BODY MASS INDEX 30 OR GREATER)·+3
NOVO NORDISK
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About Nonalcoholic steatohepatitis.

Nonalcoholic steatohepatitis is an advanced, progressive subtype of nonalcoholic fatty liver disease affecting the hepatic system, predominantly occurring in individuals with obesity, insulin resistance, type 2 diabetes, or metabolic syndrome in the absence of significant alcohol consumption.

It is histopathologically defined by hepatic steatosis accompanied by lobular inflammation and hepatocyte injury, notably ballooning degeneration, with or without associated fibrosis.

Pathophysiologically driven by lipotoxicity, oxidative stress, and immune-mediated inflammatory cascades, this condition carries a substantial risk of progressing to advanced fibrosis, cirrhosis, end-stage liver failure, and hepatocellular carcinoma.

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