Indication

Postoperative ileus

Postoperative ileus is a transient impairment of gastrointestinal motility occurring after surgery, most frequently following abdominal or pelvic procedures, in the absence of mechanical bowel obstruction. Read more about Postoperative ileus

7 drugs 7 manufacturers

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Drugs that treat it

Common Postoperative ileus therapies.

Showing 1–7 of 7 drugs

ALVIMOPAN

OPIOID ANTAGONISTS·POSTOPERATIVE ILEUS
PAR HEALTH USA,

ALVIMOPAN

OPIOID ANTAGONISTS·POSTOPERATIVE ILEUS
GSMS, INC.

ALVIMOPAN

OPIOID ANTAGONISTS·POSTOPERATIVE ILEUS
TEVA USA

ALVIMOPAN

OPIOID ANTAGONISTS·POSTOPERATIVE ILEUS
Hikma Pharmaceuticals USA
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About Postoperative ileus.

Postoperative ileus is a transient impairment of gastrointestinal motility occurring after surgery, most frequently following abdominal or pelvic procedures, in the absence of mechanical bowel obstruction.

It predominantly affects the digestive tract and is driven by a multifactorial pathophysiology involving inhibitory neural reflexes from surgical manipulation, local macrophage-mediated intestinal inflammation, and pharmacologic inhibition from perioperative opioids and anesthetics.

Clinically, it is characterized by delayed return of coordinated peristalsis, abdominal distension, nausea, vomiting, inability to tolerate oral nutrition, and delayed passage of flatus and stool.

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