Indication
Selenium deficiency
Selenium deficiency is a nutritional and metabolic disorder characterized by inadequate tissue levels of the essential trace element selenium, which impairs the synthesis and biological activity of crucial selenoproteins such as glutathione peroxidases and iodothyronine deiodinases. Read more about Selenium deficiency
9 drugs 7 manufacturers
Drugs that treat it
Common Selenium deficiency therapies.
SELENIUM
SELENIUM
SELENOMAX (selenium)
SELENIUM
SELENIUM
SELENIOUS ACID (selenium)
SELENIOUS ACID (selenium)
SELENIOUS ACID (selenium)
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Coming soonSelenium deficiency is a nutritional and metabolic disorder characterized by inadequate tissue levels of the essential trace element selenium, which impairs the synthesis and biological activity of crucial selenoproteins such as glutathione peroxidases and iodothyronine deiodinases.
This condition primarily affects the cardiovascular, musculoskeletal, endocrine, and immune systems, with higher vulnerability observed in individuals on long-term unsupplemented total parenteral nutrition, patients with severe gastrointestinal malabsorption, and populations residing in regions with selenium-poor soil.
Pathophysiologically, diminished antioxidant defenses lead to heightened cellular oxidative damage, thyroid hormone dysregulation, and altered immune response.
Clinically, it manifests as proximal muscle weakness, fatigue, myalgias, and macrocytosis, and severe chronic deficiency can result in life-threatening endemic dilated cardiomyopathy, known as Keshan disease, or deforming osteochondropathy, known as Kashin-Beck disease.
- nih.gov
Selenium deficiency is a nutritional and metabolic disorder characterized by inadequate tissue levels of the essential trace element selenium, which impairs the synthesis and biological activity of crucial selenoproteins such as glutathione peroxidases and iodothyronine deiodinases
- nih.gov
Selenium deficiency is a nutritional and metabolic disorder characterized by inadequate tissue levels of the essential trace element selenium, which impairs the synthesis and biological activity of crucial selenoproteins such as glutathione peroxidases and iodothyronine deiodinases This condition primarily affects the cardiovascular, musculoskeletal, endocrine, and immune systems, with higher vulnerability observed in individuals on long-term unsupplemented total parenteral nutrition, patients w...
- nih.gov
This condition primarily affects the cardiovascular, musculoskeletal, endocrine, and immune systems, with higher vulnerability observed in individuals on long-term unsupplemented total parenteral nutrition, patients with severe gastrointestinal malabsorption, and populations residing in regions with selenium-poor soil
- nih.gov
This condition primarily affects the cardiovascular, musculoskeletal, endocrine, and immune systems, with higher vulnerability observed in individuals on long-term unsupplemented total parenteral nutrition, patients with severe gastrointestinal malabsorption, and populations residing in regions with selenium-poor soil
- nih.gov
Clinically, it manifests as proximal muscle weakness, fatigue, myalgias, and macrocytosis, and severe chronic deficiency can result in life-threatening endemic dilated cardiomyopathy, known as Keshan disease, or deforming osteochondropathy, known as Kashin-Beck disease
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