Indication

Selenium deficiency

Selenium deficiency is a nutritional and metabolic disorder characterized by inadequate tissue levels of the essential trace element selenium, which impairs the synthesis and biological activity of crucial selenoproteins such as glutathione peroxidases and iodothyronine deiodinases. Read more about Selenium deficiency

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Drugs that treat it

Common Selenium deficiency therapies.

Showing 1–9 of 9 drugs

SELENIUM

SELENIUM·SELENIUM DEFICIENCY
CVS

SELENIUM

SELENIUM·SELENIUM DEFICIENCY
American Regent

SELENIUM

SELENIUM·SELENIUM DEFICIENCY
21ST CENTURY HE

SELENIUM

SELENIUM·SELENIUM DEFICIENCY
MASON DISTRIB.

SELENIUM

SELENIUM DEFICIENCY
GSK Consumer Healthcare
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About Selenium deficiency.

Selenium deficiency is a nutritional and metabolic disorder characterized by inadequate tissue levels of the essential trace element selenium, which impairs the synthesis and biological activity of crucial selenoproteins such as glutathione peroxidases and iodothyronine deiodinases.

This condition primarily affects the cardiovascular, musculoskeletal, endocrine, and immune systems, with higher vulnerability observed in individuals on long-term unsupplemented total parenteral nutrition, patients with severe gastrointestinal malabsorption, and populations residing in regions with selenium-poor soil.

Pathophysiologically, diminished antioxidant defenses lead to heightened cellular oxidative damage, thyroid hormone dysregulation, and altered immune response.

Clinically, it manifests as proximal muscle weakness, fatigue, myalgias, and macrocytosis, and severe chronic deficiency can result in life-threatening endemic dilated cardiomyopathy, known as Keshan disease, or deforming osteochondropathy, known as Kashin-Beck disease.

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