TURALIO (pexidartinib hydrochloride)
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS·TENOSYNOVIAL GIANT CELL TUMOR
DAIICHI SANKYO,
Indication
Tenosynovial giant cell tumor
Tenosynovial giant cell tumor is a rare, typically benign soft tissue neoplasm arising from the synovial lining of joints, bursae, and tendon sheaths. Read more about Tenosynovial giant cell tumor
2 drugs 2 manufacturers
Drugs that treat it
Common Tenosynovial giant cell tumor therapies.
ROMVIMZA (vimseltinib)
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS·TENOSYNOVIAL GIANT CELL TUMOR
DECIPHERA PHARM
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News & literature
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Coming soonTenosynovial giant cell tumor is a rare, typically benign soft tissue neoplasm arising from the synovial lining of joints, bursae, and tendon sheaths.
Primarily affecting young to middle-aged adults, it manifests along a clinicopathologic spectrum categorized into discrete localized forms, often in the digits, and infiltrative diffuse forms that commonly involve large joints such as the knee or hip.
Pathophysiologically, the tumor is characterized by genomic translocations resulting in the overexpression of colony-stimulating factor 1, which drives the accumulation of non-neoplastic macrophages, histiocytes, and multinucleated giant cells.
Although nonmalignant, progressive lesion enlargement frequently leads to pain, joint effusion, restricted range of motion, and destruction of surrounding cartilage and bone.
- cancer.gov
Tenosynovial giant cell tumor is a rare, typically benign soft tissue neoplasm arising from the synovial lining of joints, bursae, and tendon sheaths
- nih.gov
Tenosynovial giant cell tumor is a rare, typically benign soft tissue neoplasm arising from the synovial lining of joints, bursae, and tendon sheaths Primarily affecting young to middle-aged adults, it manifests along a clinicopathologic spectrum categorized into discrete localized forms, often in the digits, and infiltrative diffuse forms that commonly involve large joints such as the knee or hip
- nih.gov
Tenosynovial giant cell tumor is a rare, typically benign soft tissue neoplasm arising from the synovial lining of joints, bursae, and tendon sheaths
- mayoclinic.org
Primarily affecting young to middle-aged adults, it manifests along a clinicopathologic spectrum categorized into discrete localized forms, often in the digits, and infiltrative diffuse forms that commonly involve large joints such as the knee or hip Although nonmalignant, progressive lesion enlargement frequently leads to pain, joint effusion, restricted range of motion, and destruction of surrounding cartilage and bone
- cancer.gov
Although nonmalignant, progressive lesion enlargement frequently leads to pain, joint effusion, restricted range of motion, and destruction of surrounding cartilage and bone
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