Vernal keratitis

Vernal keratitis represents the corneal manifestation of vernal keratoconjunctivitis, a chronic, severe, and seasonally recurring allergic inflammatory disorder of the ocular surface

Vernal keratitis represents the corneal manifestation of vernal keratoconjunctivitis, a chronic, severe, and seasonally recurring allergic inflammatory disorder of the ocular surface Clinical features range from punctate epithelial erosions to non-healing sterile shield ulcers and stromal scarring, caused by the release of toxic major basic protein and mechanical microtrauma from upper tarsal giant cobblestone papillae

It primarily affects children and young adolescents, with a notable male predominance and higher prevalence in warm, dry climates or among individuals with a personal or familial history of atopy

It primarily affects children and young adolescents, with a notable male predominance and higher prevalence in warm, dry climates or among individuals with a personal or familial history of atopy

It primarily affects children and young adolescents, with a notable male predominance and higher prevalence in warm, dry climates or among individuals with a personal or familial history of atopy Clinical features range from punctate epithelial erosions to non-healing sterile shield ulcers and stromal scarring, caused by the release of toxic major basic protein and mechanical microtrauma from upper tarsal giant cobblestone papillae

Pathophysiologically driven by combined IgE-mediated (type I) and T-cell-mediated (type IV) hypersensitivity reactions, the condition involves intense eosinophil and mast cell activation

Clinical features range from punctate epithelial erosions to non-healing sterile shield ulcers and stromal scarring, caused by the release of toxic major basic protein and mechanical microtrauma from upper tarsal giant cobblestone papillae