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Physicians Office Resource's authored articles and clinical reviews, alongside curated literature and news for practical point-of-care guidance and insight.

Showing 1,993–2,004 of 2,098 articles

PubMed

Nested Continual Learning with Elastic Weight Consolidation for Progressive Alzheimer's Disease Classification from MRI.

Introduction/ Objective MRI-based Alzheimer’s staging is often modeled as separate tasks, although clinical assessment progresses from screening to more refined staging. This study developed a continual-learning framework for retaining earlier diagnostic knowledge. Methods A nested multi-head framework was implemented for sequential learning of related binary classification tasks from structural MRI slices. Because verified subject identifiers were unavailable in the Mendeley dataset, the pri...

Articles
Akgündoğdu A, Çeli̇kbaş Ş•
PubMed

Enhancing Executive Function in Adolescents With ADHD: Preliminary Findings From a Multicomponent Intervention.

Background Attention deficit hyperactivity disorder (ADHD) in adolescence is associated with executive function difficulties, which compromise academic performance, daily functioning, and adaptive behaviors. Occupational therapy is aimed at improving EF and occupation and participation impairments. This study presents preliminary findings on the effectiveness of a multicomponent intervention protocol designed to enhance cognitive abilities in adolescents with ADHD. Methods A quasi‐experimenta...

Articles
Pavlou Papagianni E, Theodorou E•
PubMed

Specific frontostriatal structural alterations underlie emotional instability but not inattention in ADHD and healthy individuals.

Background: Attention-deficit/hyperactivity disorder (ADHD) is characterized by emotional dysregulation, such as emotional instability, and by non-emotional symptoms, including inattention. These symptom domains are dimensionally distributed in the general population and are hypothesized to reflect both overlapping and distinct structural and functional features of cortical and subcortical brain networks. Methods: We applied a dimensional symptom approach in a sample of adults with ADHD (n = 71...

Articles
Klahn A, Bayard F, Abé C, Henje E, Floros O, Ingvar M, Landén M, Petrovic P•
PubMed

Long-Term Benefits of Chronic 5-HT2A Antagonist and 5-HT1A Agonist Treatment on ADHD Behavior in Juvenile Spontaneously Hypertensive Rats.

Introduction Norepinephrine and Dopamine (DA) are critical brain amines in Attention Deficit Hyperactivity Disorder (ADHD), with treatments targeting their neuroreceptors often causing adverse effects, particularly in the motor system through DA receptors. Our earlier study suggested that chronic treatment with a 5-HT1A receptor agonist or a 5-HT2A receptor antagonist in juvenile spontaneously hypertensive rats (SHRs) may improve ADHD-like symptoms by potentially modulating DA receptors. This s...

Articles
Madhyastha S, Rao MS•
PubMed

Workplace adjustments equivalent to reasonable accommodations and workplace maladjustment in a general working population, with a focus on high autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD) traits.

Background The potential effectiveness of reasonable accommodations for workers with autism spectrum disorder (ASD) and attention deficit/hyperactivity disorder (ADHD) has been reported, but quantitative evidence remains limited. It is also unclear whether ASD- or ADHD-equivalent workplace adjustments benefit workers with lower ASD or ADHD trait levels in the general population. This study aimed to quantitatively examine whether individuals with high or non-high levels of ASD or ADHD traits exp...

Articles
Suzuki T, Nakazato M, Ohtani T, Ikeda S•
PubMed

ICPi-Induced Graves' Disease with Pre-existing Autoimmune Thyroid Disorders: A Case Report and Literature Review.

Background Immune Checkpoint Inhibitor (ICPi) therapy has revolutionized cancer treatment but can lead to immune-related adverse events (irAE), including thyroid dysfunction. The impact of ICPi on patients with pre-existing autoimmune thyroid diseases (PATD), particularly the development of Graves' disease, remains poorly understood. Case Presentation We provide the first complete case of Graves' disease with ICPi therapy in a patient who already had Hashimoto's thyroiditis. The patient, a 52...

Articles
Wang X, Chen D, Shi Y, Yang T, Zheng X•
PubMed

Survival and Hemodynamic Effects of Parenteral Prostanoids in High-Altitude Group 1 Pulmonary Hypertension: A Retrospective Cohort Study.

Background In Latin America, the evidence regarding the use of prostanoids at high altitude in patients with Group 1 pulmonary hypertension (PH‐1) is limited. Therefore, it is essential to describe the clinical characteristics and outcomes associated with prostanoid treatment in this population. Methods This retrospective study involved patients with PH‐1. Hemodynamic and clinical variables were compared before the initiation of prostanoids and during clinical follow‐up. Overall survival was...

Articles
Conde-Camacho R, Tuta-Quintero E, González M, Rubiano W, Rincón E, Diaz K, Giraldo-Cadavid LF•
PubMed

Correction to "Lycopene Ameliorates Hypoxic Pulmonary Hypertension via Suppression of Oxidative Stress".

D. Wang, Y. Ji, R. Wang, et al., “Lycopene Ameliorates Hypoxic Pulmonary Hypertension via Suppression of Oxidative Stress,” Oxidative Medicine and Cellular Longevity 2022, no. 1 (2022): 9179427, https://doi.org/10.1155/2022/9179427. In the article titled, “Lycopene Ameliorates Hypoxic Pulmonary Hypertension via Suppression of Oxidative Stress,” there were multiple errors. These errors are listed below and corrected as follows: Error in the author list: The author Miaomiao Gong was omitted fro...

Articles
PubMed

Successful Pregnancy in Chronic Obstructive Pulmonary Hypertension Secondary to Pulmonary and Cardiac Hydatid Cysts: A Case Report.

Highlights Background: Pregnancy in women with pulmonary hypertension (PH) is contraindicated because of high mortality rates associated with physiological changes, particularly in the peripartum and postpartum periods. Termination is recommended early if pregnancy occurs. Consequently, clinical experience with continued pregnancy in patients with PH is scarce. Case Presentation: A 31-year-old woman was diagnosed with multiple bilateral pulmonary and right ventricular hydatid cysts. After su...

Articles
Ahmadi F, Parnia R, Astani B, Keshmiri MS, Khodadad S, Sheikhzadeh H, Daneshmandi Z, Ansari F, Riahi M, Noorali S, Yousefi-Koma H, Sharif-Kashani B, Shafaghi S•
PubMed

High-Frequency Oscillatory Ventilation Combined With Inhaled Nitric Oxide for Persistent Pulmonary Hypertension of the Newborn: A Single-Center Randomized Clinical Trial.

Background Persistent pulmonary hypertension of the newborn (PPHN) may respond incompletely to inhaled nitric oxide (iNO) when poorly recruited lung limits delivery to ventilated alveoli. We evaluated whether high‐frequency oscillatory ventilation (HFOV) combined with iNO improved clinical and physiologic outcomes compared with conventional mechanical ventilation (CMV) + iNO or HFOV alone. Methods In this prospective, single‐center, 3‐arm, open‐label randomized clinical trial, 138 neonates bo...

Articles
Wang Y, Wu Q, Zhang X, Sun Z, Zhang M, Liu X, Zhou B•
PubMed

Correction to "The Diagnostic Value of Transthoracic Echocardiography Parameters Under the New Diagnostic Criteria for Pulmonary Hypertension".

Y. Qi, J. Liu, X. Cui, et al., “The Diagnostic Value of Transthoracic Echocardiography Parameters Under the New Diagnostic Criteria for Pulmonary Hypertension,” Canadian Respiratory Journal 2025 (2025): 2592204, https://doi.org/10.1155/carj/2592204. In the article titled “The Diagnostic Value of Transthoracic Echocardiography Parameters Under the New Diagnostic Criteria for Pulmonary Hypertension,” the Author Contributions section, the statement “Yuankun Qi and Junjun Liu have contributed equal...

Articles
PubMed

The Prevalence of Intestinal Parasitic Infections in Labor Children in Karaj, Alborz Province, Iran.

Background: Child labor (CL) is the exploitation of children through any work or activity that interferes with their ability to attend school or is harmful to their mental, physical, social, or moral well-being. Unfortunately, child laborers are a shadow population for which specific information on the prevalence of intestinal parasites is not available; we aimed to estimate the prevalence of intestinal parasites among child laborers in Karaj-Alborz, Iran. Methods: The present study was condu...

Articles
Mahjoobi P, Bairami A, Heidari A, Bahadory S•