Drug class

5 Fluoropyrimidines

The 5-fluoropyrimidines (commonly referred to as fluoropyrimidines) are a class of antineoplastic antimetabolite drugs, primarily comprising 5-fluorouracil and its oral prodrugs such as capecitabine. Read more about 5 Fluoropyrimidines

34 drugs in this class 34 manufacturers

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Drugs in 5 Fluoropyrimidines

Showing 1–9 of 34 drugs

CAPECITABINE

5 FLUOROPYRIMIDINES · MALIGNANT ESOPHAGEAL NEOPLASM ·+7
TEVA USA

FLUOROURACIL

5 FLUOROPYRIMIDINES · METASTATIC COLORECTAL CANCER ·+4
APP/NOVAPLUS

FLUOROURACIL

5 FLUOROPYRIMIDINES · METASTATIC COLORECTAL CANCER ·+4
APP/PREMIERPRO

FLUOROURACIL

5 FLUOROPYRIMIDINES · METASTATIC COLORECTAL CANCER ·+4
BLUEPOINT LABOR

CAPECITABINE

5 FLUOROPYRIMIDINES · MALIGNANT ESOPHAGEAL NEOPLASM ·+7
ACCORD HEALTHCA

CAPECITABINE

5 FLUOROPYRIMIDINES · MALIGNANT ESOPHAGEAL NEOPLASM ·+7
NORTHSTAR RX LL

FLUOROURACIL

5 FLUOROPYRIMIDINES · METASTATIC COLORECTAL CANCER ·+4
APP/FRESENIUS K
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About 5 Fluoropyrimidines.

The 5-fluoropyrimidines (commonly referred to as fluoropyrimidines) are a class of antineoplastic antimetabolite drugs, primarily comprising 5-fluorouracil and its oral prodrugs such as capecitabine.

They exert their therapeutic anticancer effect predominantly by inhibiting thymidylate synthase and misincorporating fraudulent fluorinated metabolites into RNA and DNA, thereby disrupting nucleic acid synthesis and triggering cell death.

In clinical oncology, this class serves as a foundational therapeutic backbone for treating various solid tumors, most notably gastrointestinal malignancies including colorectal, gastric, and pancreatic cancers, as well as breast cancer and select hyperproliferative skin conditions.