Alpha-Blockers

Alpha-blockers, formally designated as alpha-adrenergic receptor antagonists, are a class of pharmacologic agents that selectively or nonselectively inhibit the action of norepinephrine and epinephrine at alpha-adrenergic receptors Clinically, these medications are primarily utilized to improve urinary flow in benign prostatic hyperplasia, reduce peripheral vascular resistance in essential hypertension, and control blood pressure spikes associated with pheochromocytoma

By blocking these receptors on vascular and nonvascular smooth muscle, they promote vasodilation and decrease smooth muscle tone

By blocking these receptors on vascular and nonvascular smooth muscle, they promote vasodilation and decrease smooth muscle tone