Alpha-Glucosidase Inhibitor

Alpha-glucosidase inhibitors are a class of oral antidiabetic agents used primarily in the management of type 2 diabetes mellitus and impaired glucose tolerance Prominent examples in clinical practice include acarbose and miglitol

Alpha-glucosidase inhibitors are a class of oral antidiabetic agents used primarily in the management of type 2 diabetes mellitus and impaired glucose tolerance They work by competitively inhibiting alpha-glucosidase enzymes located in the brush border of the small intestine, which delays the breakdown and digestion of complex carbohydrates into absorbable monosaccharides This slowed intestinal carbohydrate absorption blunts postprandial blood glucose spikes without directly stimulating pancreat...

They work by competitively inhibiting alpha-glucosidase enzymes located in the brush border of the small intestine, which delays the breakdown and digestion of complex carbohydrates into absorbable monosaccharides

This slowed intestinal carbohydrate absorption blunts postprandial blood glucose spikes without directly stimulating pancreatic insulin secretion