EDEX (alprostadil)
ALPROSTADIL · ERECTILE DYSFUNCTION
ENDO USA, INC.
Drug class
Alprostadil
Alprostadil is an individual active pharmaceutical ingredient—a synthetic formulation of endogenous prostaglandin E1 (PGE1)—rather than a distinct standalone therapeutic drug class. Read more about Alprostadil
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Drugs in Alprostadil
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Alprostadil is an individual active pharmaceutical ingredient—a synthetic formulation of endogenous prostaglandin E1 (PGE1)—rather than a distinct standalone therapeutic drug class.
Pharmacologically categorized as a prostaglandin vasodilator and smooth muscle relaxant, it binds to specific prostanoid receptors to elevate intracellular cyclic AMP, resulting in vascular and trabecular smooth muscle relaxation.
Clinically, it is administered locally via intracavernosal injection or intraurethral pellet to treat erectile dysfunction by promoting penile arterial inflow, and given intravenously in neonates to temporarily maintain the patency of the ductus arteriosus in ductal-dependent congenital heart defects prior to surgery.
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fda.gov
Alprostadil is an individual active pharmaceutical ingredient—a synthetic formulation of endogenous prostaglandin E1 (PGE1)—rather than a distinct standalone therapeutic drug class Pharmacologically categorized as a prostaglandin vasodilator and smooth muscle relaxant, it binds to specific prostanoid receptors to elevate intracellular cyclic AMP, resulting in vascular and trabecular smooth muscle relaxation
-
nih.gov
Alprostadil is an individual active pharmaceutical ingredient—a synthetic formulation of endogenous prostaglandin E1 (PGE1)—rather than a distinct standalone therapeutic drug class Clinically, it is administered locally via intracavernosal injection or intraurethral pellet to treat erectile dysfunction by promoting penile arterial inflow, and given intravenously in neonates to temporarily maintain the patency of the ductus arteriosus in ductal-dependent congenital heart defects prior to surgery
-
fda.gov
Pharmacologically categorized as a prostaglandin vasodilator and smooth muscle relaxant, it binds to specific prostanoid receptors to elevate intracellular cyclic AMP, resulting in vascular and trabecular smooth muscle relaxation
-
medlineplus.gov
Pharmacologically categorized as a prostaglandin vasodilator and smooth muscle relaxant, it binds to specific prostanoid receptors to elevate intracellular cyclic AMP, resulting in vascular and trabecular smooth muscle relaxation Clinically, it is administered locally via intracavernosal injection or intraurethral pellet to treat erectile dysfunction by promoting penile arterial inflow, and given intravenously in neonates to temporarily maintain the patency of the ductus arteriosus in ductal-dep...
-
nih.gov
Clinically, it is administered locally via intracavernosal injection or intraurethral pellet to treat erectile dysfunction by promoting penile arterial inflow, and given intravenously in neonates to temporarily maintain the patency of the ductus arteriosus in ductal-dependent congenital heart defects prior to surgery
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