MYTESI (crofelemer)
ANTIDIARRHEAL - GASTROINTESTINAL CHLORIDE CHANNEL INHIBITORS · DIARRHEA FROM HIV
NAPO PHARMACEUT
Drug class
Antidiarrheal - Gastrointestinal Chloride Channel Inhibitors
Gastrointestinal chloride channel inhibitors are an antidiarrheal pharmacologic class represented by locally acting antisecretory agents such as crofelemer. Read more about Antidiarrheal - Gastrointestinal Chloride Channel Inhibitors
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Gastrointestinal chloride channel inhibitors are an antidiarrheal pharmacologic class represented by locally acting antisecretory agents such as crofelemer.
Rather than altering bowel motility, these agents function by blocking luminal intestinal chloride transporters—specifically the cystic fibrosis transmembrane conductance regulator and calcium-activated chloride channels—which reduces chloride efflux and secondary fluid excretion into the gastrointestinal tract.
In clinical practice, this drug class is primarily indicated for the symptomatic relief of non-infectious diarrhea in adult patients with HIV or AIDS undergoing antiretroviral therapy.
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fda.gov
Gastrointestinal chloride channel inhibitors are an antidiarrheal pharmacologic class represented by locally acting antisecretory agents such as crofelemer
-
fda.gov
Gastrointestinal chloride channel inhibitors are an antidiarrheal pharmacologic class represented by locally acting antisecretory agents such as crofelemer Rather than altering bowel motility, these agents function by blocking luminal intestinal chloride transporters—specifically the cystic fibrosis transmembrane conductance regulator and calcium-activated chloride channels—which reduces chloride efflux and secondary fluid excretion into the gastrointestinal tract In clinical practice, this drug...
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iehp.org
Gastrointestinal chloride channel inhibitors are an antidiarrheal pharmacologic class represented by locally acting antisecretory agents such as crofelemer
-
fda.gov
Rather than altering bowel motility, these agents function by blocking luminal intestinal chloride transporters—specifically the cystic fibrosis transmembrane conductance regulator and calcium-activated chloride channels—which reduces chloride efflux and secondary fluid excretion into the gastrointestinal tract In clinical practice, this drug class is primarily indicated for the symptomatic relief of non-infectious diarrhea in adult patients with HIV or AIDS undergoing antiretroviral therapy
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