Drug class

Histamine-2 Receptor Antagonists (H2 Antagonists)

Histamine-2 receptor antagonists, commonly termed H2 antagonists or H2 blockers, are a recognized class of acid-suppressing pharmacotherapeutic agents. Read more about Histamine-2 Receptor Antagonists (H2 Antagonists)

159 drugs in this class 93 manufacturers

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Drugs in Histamine-2 Receptor Antagonists (H2 Antagonists)

Showing 1–9 of 159 drugs

FAMOTIDINE

PEPTIC ULCER AGENTS · MULTIPLE ENDOCRINE NEOPLASIA ·+13
BEDFORD LABS

NIZATIDINE

PEPTIC ULCER AGENTS · REFLUX ESOPHAGITIS ·+7
DR.REDDY'S LAB

FAMOTIDINE

PEPTIC ULCER AGENTS · MULTIPLE ENDOCRINE NEOPLASIA ·+13
LUPIN PHARMACEU
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About Histamine-2 Receptor Antagonists (H2 Antagonists).

Histamine-2 receptor antagonists, commonly termed H2 antagonists or H2 blockers, are a recognized class of acid-suppressing pharmacotherapeutic agents.

They function through competitive inhibition of histamine at the H2 receptors located on gastric parietal cells, thereby decreasing intracellular cyclic adenosine monophosphate production and markedly reducing basal and stimulated gastric acid secretion.

Clinically, members of this class are utilized to prevent and treat acid-peptic disorders, primarily gastroesophageal reflux disease, active duodenal and gastric ulcers, and pathological hypersecretory conditions such as Zollinger-Ellison syndrome.

In both prescription and over-the-counter forms, they also serve to alleviate acid indigestion and provide stress ulcer prophylaxis in hospitalized patients.