Drug class
Antidiuretic Hormone Antagonists
Antidiuretic hormone antagonists, commonly known as vasopressin receptor antagonists or vaptans, are a pharmacologic class of agents that inhibit the effects of arginine vasopressin on its target receptors. Read more about Antidiuretic Hormone Antagonists
20 drugs in this class 16 manufacturers
Drugs in Antidiuretic Hormone Antagonists
TOLVAPTAN
Antidiuretic hormone antagonists, commonly known as vasopressin receptor antagonists or vaptans, are a pharmacologic class of agents that inhibit the effects of arginine vasopressin on its target receptors.
By primarily blocking vasopressin V2 receptors in the renal collecting ducts, these drugs prevent water reabsorption and promote aquaresis—the selective excretion of solute-free water without substantial electrolyte loss.
They are clinically utilized to manage euvolemic and hypervolemic hyponatremia associated with conditions such as heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone secretion, as well as to slow kidney function decline and cyst development in rapidly progressing autosomal dominant polycystic kidney disease.
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fda.gov
Antidiuretic hormone antagonists, commonly known as vasopressin receptor antagonists or vaptans, are a pharmacologic class of agents that inhibit the effects of arginine vasopressin on its target receptors
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nih.gov
Antidiuretic hormone antagonists, commonly known as vasopressin receptor antagonists or vaptans, are a pharmacologic class of agents that inhibit the effects of arginine vasopressin on its target receptors They are clinically utilized to manage euvolemic and hypervolemic hyponatremia associated with conditions such as heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone secretion, as well as to slow kidney function decline and cyst development in rapidly progressing a...
-
nih.gov
By primarily blocking vasopressin V2 receptors in the renal collecting ducts, these drugs prevent water reabsorption and promote aquaresis—the selective excretion of solute-free water without substantial electrolyte loss
-
nih.gov
By primarily blocking vasopressin V2 receptors in the renal collecting ducts, these drugs prevent water reabsorption and promote aquaresis—the selective excretion of solute-free water without substantial electrolyte loss They are clinically utilized to manage euvolemic and hypervolemic hyponatremia associated with conditions such as heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone secretion, as well as to slow kidney function decline and cyst development in rapidl...
-
nih.gov
They are clinically utilized to manage euvolemic and hypervolemic hyponatremia associated with conditions such as heart failure, cirrhosis, and the syndrome of inappropriate antidiuretic hormone secretion, as well as to slow kidney function decline and cyst development in rapidly progressing autosomal dominant polycystic kidney disease
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