Drug class

Antifungal - Azoles Systemic

Systemic azole antifungals are synthetic antimycotic agents administered orally or parenterally to manage invasive, mucosal, and endemic fungal infections. Read more about Antifungal - Azoles Systemic

131 drugs in this class 79 manufacturers

Advertisement

Drugs in Antifungal - Azoles Systemic

Showing 19–27 of 131 drugs

VORICONAZOLE

ANTIFUNGALS-SYSTEMIC · DISSEMINATED CANDIDIASIS ·+6
SANDOZ

KETOCONAZOLE

ANTIFUNGALS-SYSTEMIC · COCCIDIOIDOMYCOSIS ·+4
TARO PHARM USA

KETOCONAZOLE

ANTIFUNGALS-SYSTEMIC · TINEA CRURIS ·+6
TARO PHARM USA

FLUCONAZOLE

ANTIFUNGALS-SYSTEMIC · ORAL CANDIDIASIS ·+11
NORTHSTAR RX LL

VORICONAZOLE

ANTIFUNGALS-SYSTEMIC · DISSEMINATED CANDIDIASIS ·+6
GREENSTONE LLC.
Filter & compare in the drug finder → Opens the drug finder with Antifungal - Azoles Systemic preselected. Add indication or manufacturer filters there.

About Antifungal - Azoles Systemic.

Systemic azole antifungals are synthetic antimycotic agents administered orally or parenterally to manage invasive, mucosal, and endemic fungal infections.

They exert their therapeutic effect by inhibiting the fungal cytochrome P450–dependent enzyme 14-alpha-demethylase, which blocks the conversion of lanosterol to ergosterol, thereby disrupting fungal cell membrane stability and inhibiting cellular growth.

Clinically, these agents—primarily triazoles such as fluconazole, itraconazole, voriconazole, and posaconazole—serve as essential therapies for systemic candidiasis, invasive aspergillosis, cryptococcal meningitis, and endemic mycoses including blastomycosis, histoplasmosis, and coccidioidomycosis, as well as for antifungal prophylaxis in immunocompromised hosts.