Drug class

Antifungal - Azoles Systemic

Systemic azole antifungals are synthetic antimycotic agents administered orally or parenterally to manage invasive, mucosal, and endemic fungal infections. Read more about Antifungal - Azoles Systemic

131 drugs in this class 79 manufacturers

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Drugs in Antifungal - Azoles Systemic

Showing 46–54 of 131 drugs

ITRACONAZOLE

ANTIFUNGALS-SYSTEMIC · TOENAIL ONYCHOMYCOSIS ·+4
ASCEND LABORATO

ITRACONAZOLE

ANTIFUNGALS-SYSTEMIC · TOENAIL ONYCHOMYCOSIS ·+4
NORTHSTAR RX LL

FLUCONAZOLE

ANTIFUNGALS-SYSTEMIC · ORAL CANDIDIASIS ·+11
ZYDUS PHARMACEU

ITRACONAZOLE

ANTIFUNGALS-SYSTEMIC · OROPHARYNGEAL CANDIDIASIS ·+1
PATRIOT PHARMAC

ITRACONAZOLE

ANTIFUNGALS-SYSTEMIC · OROPHARYNGEAL CANDIDIASIS ·+1
Amneal Pharmaceuticals

ITRACONAZOLE

ANTIFUNGALS-SYSTEMIC · TOENAIL ONYCHOMYCOSIS ·+4
TORRENT PHARMAC

FLUCONAZOLE

ANTIFUNGALS-SYSTEMIC · ORAL CANDIDIASIS ·+11
RISING PHARM

KETOCONAZOLE

ANTIFUNGALS-SYSTEMIC · COCCIDIOIDOMYCOSIS ·+4
STRIDES PHARMA
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About Antifungal - Azoles Systemic.

Systemic azole antifungals are synthetic antimycotic agents administered orally or parenterally to manage invasive, mucosal, and endemic fungal infections.

They exert their therapeutic effect by inhibiting the fungal cytochrome P450–dependent enzyme 14-alpha-demethylase, which blocks the conversion of lanosterol to ergosterol, thereby disrupting fungal cell membrane stability and inhibiting cellular growth.

Clinically, these agents—primarily triazoles such as fluconazole, itraconazole, voriconazole, and posaconazole—serve as essential therapies for systemic candidiasis, invasive aspergillosis, cryptococcal meningitis, and endemic mycoses including blastomycosis, histoplasmosis, and coccidioidomycosis, as well as for antifungal prophylaxis in immunocompromised hosts.