Drug class

Antifungals-Systemic

Systemic antifungals comprise a diverse therapeutic group of medications administered orally or parenterally to treat internal, invasive, or severe fungal infections throughout the body. Read more about Antifungals-Systemic

205 drugs in this class 99 manufacturers

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Drugs in Antifungals-Systemic

Showing 73–81 of 205 drugs

KETOCONAZOLE

ANTIFUNGALS-SYSTEMIC · COCCIDIOIDOMYCOSIS ·+4
STRIDES PHARMA

VORICONAZOLE

ANTIFUNGALS-SYSTEMIC · DISSEMINATED CANDIDIASIS ·+6
SLATE RUN PHARM

FLUCYTOSINE

ANTIFUNGALS-SYSTEMIC · CANDIDAL URINARY TRACT INFECTION ·+2
Major Pharamceuticals

VORICONAZOLE

ANTIFUNGALS-SYSTEMIC · DISSEMINATED CANDIDIASIS ·+6
VIONA PHARMACEU

VORICONAZOLE

ANTIFUNGALS-SYSTEMIC · DISSEMINATED CANDIDIASIS ·+6
SANDOZ
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About Antifungals-Systemic.

Systemic antifungals comprise a diverse therapeutic group of medications administered orally or parenterally to treat internal, invasive, or severe fungal infections throughout the body.

Spanning multiple chemical classes—including triazoles, echinocandins, polyenes, and allylamines—these agents exert fungicidal or fungistatic activity by disrupting vital fungal cell structures, primarily by inhibiting ergosterol biosynthesis, binding directly to membrane ergosterol, or blocking fungal cell wall synthesis.

Clinically, systemic antifungals are essential for treating life-threatening invasive candidiasis, invasive aspergillosis, cryptococcal meningitis, and endemic mycoses, as well as managing recalcitrant mucocutaneous infections and providing targeted prophylaxis in immunocompromised patient populations.