Drug class

Antihyperlipidemics - Nicotinic Acid and Derivatives

Antihyperlipidemics – Nicotinic Acid and Derivatives constitutes a recognized therapeutic class of lipid-modifying agents that includes nicotinic acid (niacin) and related chemical analogues such as acipimox. Read more about Antihyperlipidemics - Nicotinic Acid and Derivatives

12 drugs in this class 12 manufacturers

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Drugs in Antihyperlipidemics - Nicotinic Acid and Derivatives

Showing 10–12 of 12 drugs

NIACIN ER (niacin)

NIACIN/NIACINAMIDE (VITAMIN B-3) · HYPERCHOLESTEROLEMIA ·+6
CHARTWELL RX LL

NIACIN

NIACIN/NIACINAMIDE (VITAMIN B-3) · HYPERCHOLESTEROLEMIA ·+6
REDMONT PHARMAC

NIACIN ER (niacin)

NIACIN/NIACINAMIDE (VITAMIN B-3) · HYPERCHOLESTEROLEMIA ·+6
Lannett Company
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About Antihyperlipidemics - Nicotinic Acid and Derivatives.

Antihyperlipidemics – Nicotinic Acid and Derivatives constitutes a recognized therapeutic class of lipid-modifying agents that includes nicotinic acid (niacin) and related chemical analogues such as acipimox.

At pharmacological doses, these agents primarily act by activating hydroxycarboxylic acid receptor 2 (HCA2/GPR109A) in adipose tissue to inhibit lipolysis, thereby decreasing circulating free fatty acid flux to the liver, attenuating hepatic synthesis of very-low-density lipoproteins and triglycerides, and raising high-density lipoprotein cholesterol.

Clinically, this drug class is primarily used as an adjunct to diet in the management of dyslipidemia, mixed dyslipidemia, and severe hypertriglyceridemia, as well as to lower cardiovascular risk in selected patient populations.