Drug class

Antineoplastic - Anti-Programmed Death-(PD-1/L1) MC Antibody

The phrase "Antineoplastic - Anti-Programmed Death-(PD-1/L1) MC Antibody" represents a compendial and formulary drug classification used by standardized drug databases to group antineoplastic monoclonal antibodies that target the PD-1/PD-L1 checkpoint axis. Read more about Antineoplastic - Anti-Programmed Death-(PD-1/L1) MC Antibody

14 drugs in this class 11 manufacturers

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Drugs in Antineoplastic - Anti-Programmed Death-(PD-1/L1) MC Antibody

Showing 1–9 of 14 drugs

LIBTAYO (cemiplimab-rwlc)

ANTINEOPLASTIC - ANTI-PROGRAMMED DEATH-(PD-1/L1) MC ANTIBODY · BASAL CELL CARCINOMA OF SKIN ·+3
Regeneron Pharmaceuticals, Inc.
Sponsored

OPDIVO (nivolumab)

ANTINEOPLASTIC - ANTI-PROGRAMMED DEATH-(PD-1/L1) MC ANTIBODY · MALIGNANT ESOPHAGEAL NEOPLASM ·+17
BMS PRIMARYCARE

KEYTRUDA (pembrolizumab)

ANTINEOPLASTIC - ANTI-PROGRAMMED DEATH-(PD-1/L1) MC ANTIBODY · MALIGNANT MELANOMA ·+36
Merck Sharp & Dohme

TECENTRIQ (atezolizumab)

ANTINEOPLASTIC - ANTI-PROGRAMMED DEATH-(PD-1/L1) MC ANTIBODY · SMALL CELL LUNG CARCINOMA ·+8
GENENTECH

BAVENCIO (avelumab)

ANTINEOPLASTIC - ANTI-PROGRAMMED DEATH-(PD-1/L1) MC ANTIBODY · RENAL CELL CARCINOMA ·+2
EMD SERONO, INC

IMFINZI (durvalumab)

ANTINEOPLASTIC - ANTI-PROGRAMMED DEATH-(PD-1/L1) MC ANTIBODY · BILIARY TRACT MALIGNANCY ·+10
AstraZeneca Pharmaceuticals

ZYNYZ (retifanlimab-dlwr)

ANTINEOPLASTIC - ANTI-PROGRAMMED DEATH-(PD-1/L1) MC ANTIBODY · MERKEL CELL CARCINOMA ·+1
Incyte Corporation
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About Antineoplastic - Anti-Programmed Death-(PD-1/L1) MC Antibody.

The phrase "Antineoplastic - Anti-Programmed Death-(PD-1/L1) MC Antibody" represents a compendial and formulary drug classification used by standardized drug databases to group antineoplastic monoclonal antibodies that target the PD-1/PD-L1 checkpoint axis.

Clinically recognized as immune checkpoint inhibitors, these therapeutic antibodies bind directly to either programmed cell death protein 1 on T cells or programmed death-ligand 1 on tumor and immune-infiltrating cells.

By disrupting this inhibitory pathway, the agents overcome tumor-mediated immunosuppression and restore host T-cell–mediated antitumor immune responses.

Monoclonal antibodies in this therapeutic class are widely indicated across medical oncology for diverse malignancies, including non-small cell lung cancer, melanoma, renal cell carcinoma, urothelial carcinoma, and tumors displaying high microsatellite instability or mismatch repair deficiency.