AVOPEF (etoposide)
ANTINEOPLASTIC - EPIPODOPHYLLOTOXINS · SMALL CELL LUNG CARCINOMA ·+1
AVYXA PHARMA, L
Drug class
Antineoplastic - Epipodophyllotoxins
Antineoplastic epipodophyllotoxins are a class of semisynthetic plant alkaloid cytotoxic agents derived from the mandrake plant (*Podophyllum peltatum*). Read more about Antineoplastic - Epipodophyllotoxins
11 drugs in this class 11 manufacturers
Drugs in Antineoplastic - Epipodophyllotoxins
VEPESID (etoposide)
ANTINEOPLASTIC - EPIPODOPHYLLOTOXINS · SMALL CELL LUNG CARCINOMA
Amneal Pharmaceuticals
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Antineoplastic epipodophyllotoxins are a class of semisynthetic plant alkaloid cytotoxic agents derived from the mandrake plant (*Podophyllum peltatum*).
They primarily function as topoisomerase II poisons, stabilizing enzyme-DNA cleavage complexes and inducing double- and single-stranded DNA breaks that trigger cell cycle arrest and apoptosis.
Members of this class, most notably etoposide and teniposide, serve as critical components of combination chemotherapy regimens across several hematologic and solid malignancies.
Major disease indications include refractory testicular cancer, small cell lung cancer, acute leukemias (particularly childhood acute lymphoblastic leukemia), and malignant lymphomas.
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cancer.gov
Antineoplastic epipodophyllotoxins are a class of semisynthetic plant alkaloid cytotoxic agents derived from the mandrake plant (*Podophyllum peltatum*)
-
nih.gov
Antineoplastic epipodophyllotoxins are a class of semisynthetic plant alkaloid cytotoxic agents derived from the mandrake plant (*Podophyllum peltatum*)
-
cancer.gov
Antineoplastic epipodophyllotoxins are a class of semisynthetic plant alkaloid cytotoxic agents derived from the mandrake plant (*Podophyllum peltatum*) They primarily function as topoisomerase II poisons, stabilizing enzyme-DNA cleavage complexes and inducing double- and single-stranded DNA breaks that trigger cell cycle arrest and apoptosis
-
nih.gov
They primarily function as topoisomerase II poisons, stabilizing enzyme-DNA cleavage complexes and inducing double- and single-stranded DNA breaks that trigger cell cycle arrest and apoptosis Major disease indications include refractory testicular cancer, small cell lung cancer, acute leukemias (particularly childhood acute lymphoblastic leukemia), and malignant lymphomas
-
cancer.gov
Members of this class, most notably etoposide and teniposide, serve as critical components of combination chemotherapy regimens across several hematologic and solid malignancies
-
cancer.gov
Members of this class, most notably etoposide and teniposide, serve as critical components of combination chemotherapy regimens across several hematologic and solid malignancies
-
nih.gov
Members of this class, most notably etoposide and teniposide, serve as critical components of combination chemotherapy regimens across several hematologic and solid malignancies
-
cancer.gov
Major disease indications include refractory testicular cancer, small cell lung cancer, acute leukemias (particularly childhood acute lymphoblastic leukemia), and malignant lymphomas
-
nih.gov
Major disease indications include refractory testicular cancer, small cell lung cancer, acute leukemias (particularly childhood acute lymphoblastic leukemia), and malignant lymphomas
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