Drug class

Antineoplastic - Immunotherapy, T-cell Engager

Antineoplastic T-cell engager immunotherapies are engineered multispecific biologic agents designed to redirect endogenous cytotoxic T cells to destroy malignant cells. Read more about Antineoplastic - Immunotherapy, T-cell Engager

14 drugs in this class 8 manufacturers

Advertisement

Drugs in Antineoplastic - Immunotherapy, T-cell Engager

Showing 10–14 of 14 drugs

Filter & compare in the drug finder → Opens the drug finder with Antineoplastic - Immunotherapy, T-cell Engager preselected. Add indication or manufacturer filters there.

About Antineoplastic - Immunotherapy, T-cell Engager.

Antineoplastic T-cell engager immunotherapies are engineered multispecific biologic agents designed to redirect endogenous cytotoxic T cells to destroy malignant cells.

Their primary mechanism of action involves simultaneously binding to the CD3 subunit of the T-cell receptor complex and a specific tumor-associated antigen, forming an immunological synapse that triggers targeted, MHC-independent cytolytic killing.

These therapies are widely utilized in the treatment of hematologic malignancies, such as acute lymphoblastic leukemia, multiple myeloma, and non-Hodgkin lymphomas, as well as selected solid tumors including small cell lung cancer and uveal melanoma.