Drug class

Antineoplastic - Proteasome Enzyme Inhibitors

Antineoplastic proteasome enzyme inhibitors are a class of targeted anticancer therapies that disrupt intracellular protein degradation by inhibiting the enzymatic core of the 26S proteasome complex. Read more about Antineoplastic - Proteasome Enzyme Inhibitors

22 drugs in this class 21 manufacturers

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Drugs in Antineoplastic - Proteasome Enzyme Inhibitors

Showing 1–9 of 22 drugs

VELCADE (bortezomib)

ANTINEOPLASTIC - PROTEASOME ENZYME INHIBITORS · MULTIPLE MYELOMA ·+1
MILLENNIUM PHAR

BORTEZOMIB

ANTINEOPLASTIC - PROTEASOME ENZYME INHIBITORS · MULTIPLE MYELOMA ·+1
FRESENIUS KABI

BORTEZOMIB

ANTINEOPLASTIC - PROTEASOME ENZYME INHIBITORS · MULTIPLE MYELOMA ·+1
DR.REDDY'S LAB

BORTEZOMIB

ANTINEOPLASTIC - PROTEASOME ENZYME INHIBITORS · MULTIPLE MYELOMA ·+1
NORTHSTAR RX LL

BORTEZOMIB

ANTINEOPLASTIC - PROTEASOME ENZYME INHIBITORS · MULTIPLE MYELOMA ·+1
SAGENT PHARMACE

BORTEZOMIB

ANTINEOPLASTIC - PROTEASOME ENZYME INHIBITORS · MULTIPLE MYELOMA ·+1
CAMBER PHARMACE

BORTEZOMIB

ANTINEOPLASTIC - PROTEASOME ENZYME INHIBITORS · MULTIPLE MYELOMA ·+1
EUGIA US LLC
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About Antineoplastic - Proteasome Enzyme Inhibitors.

Antineoplastic proteasome enzyme inhibitors are a class of targeted anticancer therapies that disrupt intracellular protein degradation by inhibiting the enzymatic core of the 26S proteasome complex.

By blocking the targeted breakdown of polyubiquitinated regulatory and damaged proteins, these agents trigger toxic intracellular protein accumulation, endoplasmic reticulum stress, cell-cycle arrest, and apoptosis in rapidly dividing cells.

This therapeutic class is primarily indicated for the treatment of hematologic malignancies, serving as a foundational component in regimens for multiple myeloma and mantle cell lymphoma.