GEFITINIB
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS · METASTATIC NON-SMALL CELL LUNG CANCER WITH EGFR EXON 21 L858R SUBSTITUTION MUTATION ·+1
INGENUS PHARMAC
Drug class
Antineoplastic - Protein-Tyrosine Kinase Inhibitors
Antineoplastic protein-tyrosine kinase inhibitors are a targeted therapeutic class of predominantly small-molecule agents designed to treat diverse malignancies. Read more about Antineoplastic - Protein-Tyrosine Kinase Inhibitors
170 drugs in this class 83 manufacturers
Drugs in Antineoplastic - Protein-Tyrosine Kinase Inhibitors
DASATINIB
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS · PHILADELPHIA CHROMOSOME POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA ·+4
DR.REDDY'S LAB
SORAFENIB (sorafenib tosylate)
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS · RENAL CELL CARCINOMA ·+2
DR.REDDY'S LAB
SUNITINIB MALATE
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS · RENAL CELL CARCINOMA ·+3
DR.REDDY'S LAB
LAZCLUZE (lazertinib mesylate)
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS · NON-SMALL CELL LUNG CANCER WITH EGFR EXON 19 DELETION ·+1
JANSSEN BIOTECH, Inc.
ERLOTINIB HCL
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS · ADENOCARCINOMA OF PANCREAS ·+2
AREVA PHARMACEU
IMATINIB MESYLATE
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS · PHILADELPHIA CHROMOSOME POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA ·+11
AREVA PHARMACEU
IMATINIB MESYLATE
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS · PHILADELPHIA CHROMOSOME POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA ·+11
GSMS, INC.
PAZOPANIB HCL
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS · SOFT OR CONNECTIVE TISSUE SARCOMA ·+1
GSMS, INC.
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Antineoplastic protein-tyrosine kinase inhibitors are a targeted therapeutic class of predominantly small-molecule agents designed to treat diverse malignancies.
They function by competitively inhibiting the adenosine triphosphate (ATP)–binding sites or allosteric regulatory domains of receptor and non-receptor tyrosine kinases, thereby disrupting downstream intracellular signaling cascades essential for oncogenic cell proliferation, survival, and angiogenesis.
Clinically, these agents play a foundational role in managing both hematologic neoplasms, such as chronic myeloid leukemia, and a broad range of solid tumors, including non-small cell lung cancer, renal cell carcinoma, gastrointestinal stromal tumors, and breast cancer.
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nih.gov
Antineoplastic protein-tyrosine kinase inhibitors are a targeted therapeutic class of predominantly small-molecule agents designed to treat diverse malignancies Clinically, these agents play a foundational role in managing both hematologic neoplasms, such as chronic myeloid leukemia, and a broad range of solid tumors, including non-small cell lung cancer, renal cell carcinoma, gastrointestinal stromal tumors, and breast cancer
-
nih.gov
Antineoplastic protein-tyrosine kinase inhibitors are a targeted therapeutic class of predominantly small-molecule agents designed to treat diverse malignancies They function by competitively inhibiting the adenosine triphosphate (ATP)–binding sites or allosteric regulatory domains of receptor and non-receptor tyrosine kinases, thereby disrupting downstream intracellular signaling cascades essential for oncogenic cell proliferation, survival, and angiogenesis
-
nih.gov
They function by competitively inhibiting the adenosine triphosphate (ATP)–binding sites or allosteric regulatory domains of receptor and non-receptor tyrosine kinases, thereby disrupting downstream intracellular signaling cascades essential for oncogenic cell proliferation, survival, and angiogenesis
-
rxlist.com
Clinically, these agents play a foundational role in managing both hematologic neoplasms, such as chronic myeloid leukemia, and a broad range of solid tumors, including non-small cell lung cancer, renal cell carcinoma, gastrointestinal stromal tumors, and breast cancer
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