IBTROZI (taletrectinib adipate)
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS · ROS1 POSITIVE NON-SMALL CELL LUNG CANCER
NUVATION BIO IN
Drug class
Antineoplastic - Protein-Tyrosine Kinase Inhibitors
Antineoplastic protein-tyrosine kinase inhibitors are a targeted therapeutic class of predominantly small-molecule agents designed to treat diverse malignancies. Read more about Antineoplastic - Protein-Tyrosine Kinase Inhibitors
170 drugs in this class 83 manufacturers
Drugs in Antineoplastic - Protein-Tyrosine Kinase Inhibitors
SUNITINIB MALATE
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS · RENAL CELL CARCINOMA ·+3
NOVADOZ PHARMAC
HERNEXEOS (zongertinib)
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS · HER2 POSITIVE NON-SQUAMOUS NON-SMALL CELL LUNG CANCER W/ TYROSINE KINASE DOMAIN ACTIVATING MUTATIONS
Boehringer Ingelheim
PHYRAGO (dasatinib)
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS · PHILADELPHIA CHROMOSOME POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA ·+4
CYCLE PHARMACEU
DASATINIB
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS · PHILADELPHIA CHROMOSOME POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA ·+4
BLUEPOINT/ONCOP
DASATINIB
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS · PHILADELPHIA CHROMOSOME POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA ·+4
TEVA PHARM
IMATINIB MESYLATE
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS · PHILADELPHIA CHROMOSOME POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA ·+11
CAMBER PHARMACE
NILOTINIB HCL
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS · CHRONIC PHASE PHILADELPHIA CHROMOSOME POSITIVE CHRONIC MYELOCYTIC LEUKEMIA ·+1
DR.REDDY'S LAB
NILOTINIB HCL
ANTINEOPLASTIC - PROTEIN-TYROSINE KINASE INHIBITORS · CHRONIC PHASE PHILADELPHIA CHROMOSOME POSITIVE CHRONIC MYELOCYTIC LEUKEMIA ·+1
CAMBER PHARMACE
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Antineoplastic protein-tyrosine kinase inhibitors are a targeted therapeutic class of predominantly small-molecule agents designed to treat diverse malignancies.
They function by competitively inhibiting the adenosine triphosphate (ATP)–binding sites or allosteric regulatory domains of receptor and non-receptor tyrosine kinases, thereby disrupting downstream intracellular signaling cascades essential for oncogenic cell proliferation, survival, and angiogenesis.
Clinically, these agents play a foundational role in managing both hematologic neoplasms, such as chronic myeloid leukemia, and a broad range of solid tumors, including non-small cell lung cancer, renal cell carcinoma, gastrointestinal stromal tumors, and breast cancer.
-
nih.gov
Antineoplastic protein-tyrosine kinase inhibitors are a targeted therapeutic class of predominantly small-molecule agents designed to treat diverse malignancies Clinically, these agents play a foundational role in managing both hematologic neoplasms, such as chronic myeloid leukemia, and a broad range of solid tumors, including non-small cell lung cancer, renal cell carcinoma, gastrointestinal stromal tumors, and breast cancer
-
nih.gov
Antineoplastic protein-tyrosine kinase inhibitors are a targeted therapeutic class of predominantly small-molecule agents designed to treat diverse malignancies They function by competitively inhibiting the adenosine triphosphate (ATP)–binding sites or allosteric regulatory domains of receptor and non-receptor tyrosine kinases, thereby disrupting downstream intracellular signaling cascades essential for oncogenic cell proliferation, survival, and angiogenesis
-
nih.gov
They function by competitively inhibiting the adenosine triphosphate (ATP)–binding sites or allosteric regulatory domains of receptor and non-receptor tyrosine kinases, thereby disrupting downstream intracellular signaling cascades essential for oncogenic cell proliferation, survival, and angiogenesis
-
rxlist.com
Clinically, these agents play a foundational role in managing both hematologic neoplasms, such as chronic myeloid leukemia, and a broad range of solid tumors, including non-small cell lung cancer, renal cell carcinoma, gastrointestinal stromal tumors, and breast cancer
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