Drug class
Calcimimetic, Parathyroid Calcium Recep Sensitivity Enhancer
Calcimimetics, parathyroid calcium receptor sensitivity enhancers, are a therapeutic class of agents that directly lower parathyroid hormone levels by increasing the sensitivity of calcium-sensing receptors on parathyroid cells to activation by extracellular calcium. Read more about Calcimimetic, Parathyroid Calcium Recep Sensitivity Enhancer
19 drugs in this class 15 manufacturers
Drugs in Calcimimetic, Parathyroid Calcium Recep Sensitivity Enhancer
CINACALCET HCL
CINACALCET HCL
CINACALCET HCL
CINACALCET HCL
CINACALCET HCL
CINACALCET HCL
CINACALCET HCL
CINACALCET HCL
Calcimimetics, parathyroid calcium receptor sensitivity enhancers, are a therapeutic class of agents that directly lower parathyroid hormone levels by increasing the sensitivity of calcium-sensing receptors on parathyroid cells to activation by extracellular calcium.
By allosterically enhancing receptor activation at lower ambient calcium concentrations, these drugs suppress parathyroid hormone secretion and subsequently decrease serum calcium and phosphorus concentrations.
Clinically, medications in this class—such as cinacalcet and etelcalcetide—are primarily used to manage secondary hyperparathyroidism in patients with chronic kidney disease on dialysis, as well as severe hypercalcemia in individuals with primary hyperparathyroidism or parathyroid carcinoma.
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fda.gov
Calcimimetics, parathyroid calcium receptor sensitivity enhancers, are a therapeutic class of agents that directly lower parathyroid hormone levels by increasing the sensitivity of calcium-sensing receptors on parathyroid cells to activation by extracellular calcium By allosterically enhancing receptor activation at lower ambient calcium concentrations, these drugs suppress parathyroid hormone secretion and subsequently decrease serum calcium and phosphorus concentrations Clinically, medications...
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amgen.com
Calcimimetics, parathyroid calcium receptor sensitivity enhancers, are a therapeutic class of agents that directly lower parathyroid hormone levels by increasing the sensitivity of calcium-sensing receptors on parathyroid cells to activation by extracellular calcium
-
wikipedia.org
Calcimimetics, parathyroid calcium receptor sensitivity enhancers, are a therapeutic class of agents that directly lower parathyroid hormone levels by increasing the sensitivity of calcium-sensing receptors on parathyroid cells to activation by extracellular calcium Clinically, medications in this class—such as cinacalcet and etelcalcetide—are primarily used to manage secondary hyperparathyroidism in patients with chronic kidney disease on dialysis, as well as severe hypercalcemia in individuals...
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nih.gov
By allosterically enhancing receptor activation at lower ambient calcium concentrations, these drugs suppress parathyroid hormone secretion and subsequently decrease serum calcium and phosphorus concentrations
-
fda.gov
Clinically, medications in this class—such as cinacalcet and etelcalcetide—are primarily used to manage secondary hyperparathyroidism in patients with chronic kidney disease on dialysis, as well as severe hypercalcemia in individuals with primary hyperparathyroidism or parathyroid carcinoma
-
fda.gov
Clinically, medications in this class—such as cinacalcet and etelcalcetide—are primarily used to manage secondary hyperparathyroidism in patients with chronic kidney disease on dialysis, as well as severe hypercalcemia in individuals with primary hyperparathyroidism or parathyroid carcinoma
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