DEXRAZOXANE (dexrazoxane HCl)
CHEMOPROTECTIVES - CARDIOPROTECTIVE INTRACELLULAR CHELATORS · DOXORUBICIN-INDUCED CARDIOMYOPATHY
ALMAJECT-NOVAPL
Drug class
Chemoprotectives - Agents for Chemotherapy Extravasation
The phrase "Chemoprotectives - Agents for Chemotherapy Extravasation" refers to an administrative drug classification rather than a formal standalone pharmacologic class, encompassing antidote and cytoprotective therapies used to mitigate local tissue damage following accidental extravasation of vesicant antineoplastic drugs. Read more about Chemoprotectives - Agents for Chemotherapy Extravasation
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Drugs in Chemoprotectives - Agents for Chemotherapy Extravasation
DEXRAZOXANE (dexrazoxane HCl)
CHEMOPROTECTIVES - CARDIOPROTECTIVE INTRACELLULAR CHELATORS · DOXORUBICIN-INDUCED CARDIOMYOPATHY
NOVADOZ PHARMAC
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The phrase "Chemoprotectives - Agents for Chemotherapy Extravasation" refers to an administrative drug classification rather than a formal standalone pharmacologic class, encompassing antidote and cytoprotective therapies used to mitigate local tissue damage following accidental extravasation of vesicant antineoplastic drugs.
The primary therapeutic agent in this category is dexrazoxane, an intracellular chelating agent and topoisomerase II inhibitor that prevents anthracycline-mediated tissue necrosis.
Additional supportive agents, such as hyaluronidase or sodium thiosulfate, function enzymatically or chemically to disperse or neutralize extravasated vinca alkaloids or alkylating agents.
These therapies are utilized specifically in oncology supportive care to manage accidental perivascular infiltration during the treatment of various solid tumors and hematologic malignancies.
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nih.gov
The phrase "Chemoprotectives - Agents for Chemotherapy Extravasation" refers to an administrative drug classification rather than a formal standalone pharmacologic class, encompassing antidote and cytoprotective therapies used to mitigate local tissue damage following accidental extravasation of vesicant antineoplastic drugs The primary therapeutic agent in this category is dexrazoxane, an intracellular chelating agent and topoisomerase II inhibitor that prevents anthracycline-mediated tissue ne...
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researchgate.net
The phrase "Chemoprotectives - Agents for Chemotherapy Extravasation" refers to an administrative drug classification rather than a formal standalone pharmacologic class, encompassing antidote and cytoprotective therapies used to mitigate local tissue damage following accidental extravasation of vesicant antineoplastic drugs The primary therapeutic agent in this category is dexrazoxane, an intracellular chelating agent and topoisomerase II inhibitor that prevents anthracycline-mediated tissue ne...
-
edaegypt.gov.eg
Additional supportive agents, such as hyaluronidase or sodium thiosulfate, function enzymatically or chemically to disperse or neutralize extravasated vinca alkaloids or alkylating agents
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science.gov
Additional supportive agents, such as hyaluronidase or sodium thiosulfate, function enzymatically or chemically to disperse or neutralize extravasated vinca alkaloids or alkylating agents These therapies are utilized specifically in oncology supportive care to manage accidental perivascular infiltration during the treatment of various solid tumors and hematologic malignancies
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