Drug class

Choleretics

Choleretics are a functional pharmacological class of agents that stimulate the hepatic production and secretion of bile. Read more about Choleretics

1 drugs in this class 1 manufacturers

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Drugs in Choleretics

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CHOLBAM (cholic acid)

CHOLERETICS · DEFICIENCY OF BILE ACIDS DUE TO PEROXISOMAL DISORDER ·+1
MIRUM PHARMACEU
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About Choleretics.

Choleretics are a functional pharmacological class of agents that stimulate the hepatic production and secretion of bile.

By enhancing bile acid-dependent or bile acid-independent biliary flow, these substances increase the volume of bile entering the biliary canaliculi, facilitating the clearance of cytotoxic compounds and lipid solubilization.

While traditional physiology distinguishes choleretics from cholagogues, modern therapeutic classification systems—such as the National Library of Medicine Medical Subject Headings and World Health Organization Anatomical Therapeutic Chemical groupings—typically categorize these agents alongside bile acids and related biliary therapies.

Clinically, drugs exhibiting choleretic activity, most notably hydrophilic bile acids like ursodeoxycholic acid, are primarily utilized in hepatology to manage chronic cholestatic liver diseases, including primary biliary cholangitis, and to facilitate the dissolution or prevention of radiolucent gallstones.