Drug class
Cyclic Lipopeptides
Cyclic lipopeptides are a distinct class of antibacterial agents characterized by a cyclic peptide core attached to a lipophilic fatty acid tail. Read more about Cyclic Lipopeptides
25 drugs in this class 25 manufacturers
Drugs in Cyclic Lipopeptides
DAPTOMYCIN
DAPTOMYCIN
DAPTOMYCIN
DAPTOMYCIN
DAPTOMYCIN
DAPTOMYCIN
Cyclic lipopeptides are a distinct class of antibacterial agents characterized by a cyclic peptide core attached to a lipophilic fatty acid tail.
They exert rapid, concentration-dependent bactericidal activity primarily by inserting into bacterial cell membranes in a calcium-dependent manner, triggering rapid membrane depolarization, disruption of membrane integrity, and subsequent arrest of essential cellular synthesis pathways.
In clinical practice, this class—principally represented by daptomycin—is reserved for serious infections caused by multidrug-resistant Gram-positive pathogens.
Major therapeutic applications include complicated skin and skin structure infections, *Staphylococcus aureus* bacteremia, and right-sided infective endocarditis.
-
fda.gov
Cyclic lipopeptides are a distinct class of antibacterial agents characterized by a cyclic peptide core attached to a lipophilic fatty acid tail
-
nih.gov
Cyclic lipopeptides are a distinct class of antibacterial agents characterized by a cyclic peptide core attached to a lipophilic fatty acid tail
-
fda.gov
They exert rapid, concentration-dependent bactericidal activity primarily by inserting into bacterial cell membranes in a calcium-dependent manner, triggering rapid membrane depolarization, disruption of membrane integrity, and subsequent arrest of essential cellular synthesis pathways
-
fda.gov
They exert rapid, concentration-dependent bactericidal activity primarily by inserting into bacterial cell membranes in a calcium-dependent manner, triggering rapid membrane depolarization, disruption of membrane integrity, and subsequent arrest of essential cellular synthesis pathways In clinical practice, this class—principally represented by daptomycin—is reserved for serious infections caused by multidrug-resistant Gram-positive pathogens
-
nih.gov
They exert rapid, concentration-dependent bactericidal activity primarily by inserting into bacterial cell membranes in a calcium-dependent manner, triggering rapid membrane depolarization, disruption of membrane integrity, and subsequent arrest of essential cellular synthesis pathways
-
nih.gov
In clinical practice, this class—principally represented by daptomycin—is reserved for serious infections caused by multidrug-resistant Gram-positive pathogens
-
fda.gov
Major therapeutic applications include complicated skin and skin structure infections, *Staphylococcus aureus* bacteremia, and right-sided infective endocarditis
-
fda.gov
Major therapeutic applications include complicated skin and skin structure infections, *Staphylococcus aureus* bacteremia, and right-sided infective endocarditis
Sign in to follow this class
Following a drug class requires a free Physicians Office Resource account.