Drug class

Cyclic Lipopeptides

Cyclic lipopeptides are a distinct class of antibacterial agents characterized by a cyclic peptide core attached to a lipophilic fatty acid tail. Read more about Cyclic Lipopeptides

25 drugs in this class 25 manufacturers

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Drugs in Cyclic Lipopeptides

Showing 19–25 of 25 drugs

DAPTOMYCIN

AGENTS TO TREAT RESISTANT GRAM POSITIVE ORGANISMS · STAPHYLOCOCCUS AUREUS SEPTICEMIA ·+6
MEITHEAL-NOVAPL

DAPTOMYCIN

AGENTS TO TREAT RESISTANT GRAM POSITIVE ORGANISMS · STAPHYLOCOCCUS AUREUS SEPTICEMIA ·+6
MEITHEAL-HEALTH

DAPTOMYCIN

AGENTS TO TREAT RESISTANT GRAM POSITIVE ORGANISMS · STAPHYLOCOCCUS AUREUS SEPTICEMIA ·+6
Hikma Pharmaceuticals USA

DAPTOMYCIN

AGENTS TO TREAT RESISTANT GRAM POSITIVE ORGANISMS · STAPHYLOCOCCUS AUREUS SEPTICEMIA ·+6
ENDO USA, INC.

DAPTOMYCIN

AGENTS TO TREAT RESISTANT GRAM POSITIVE ORGANISMS · STAPHYLOCOCCUS AUREUS SEPTICEMIA ·+6
Hikma Pharmaceuticals USA

DAPTOMYCIN

AGENTS TO TREAT RESISTANT GRAM POSITIVE ORGANISMS · STAPHYLOCOCCUS AUREUS SEPTICEMIA ·+6
Hikma Pharmaceuticals USA

DAPTOMYCIN

AGENTS TO TREAT RESISTANT GRAM POSITIVE ORGANISMS · STAPHYLOCOCCUS AUREUS SEPTICEMIA ·+6
Endo USA
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About Cyclic Lipopeptides.

Cyclic lipopeptides are a distinct class of antibacterial agents characterized by a cyclic peptide core attached to a lipophilic fatty acid tail.

They exert rapid, concentration-dependent bactericidal activity primarily by inserting into bacterial cell membranes in a calcium-dependent manner, triggering rapid membrane depolarization, disruption of membrane integrity, and subsequent arrest of essential cellular synthesis pathways.

In clinical practice, this class—principally represented by daptomycin—is reserved for serious infections caused by multidrug-resistant Gram-positive pathogens.

Major therapeutic applications include complicated skin and skin structure infections, *Staphylococcus aureus* bacteremia, and right-sided infective endocarditis.