Digitalis Glycosides

Digitalis glycosides, also referred to as cardiac glycosides, are a class of naturally derived cardiovascular agents—most notably digoxin—traditionally extracted from digitalis plants They act primarily by reversibly inhibiting myocardial sodium-potassium adenosine triphosphatase (Na+/K+-ATPase), which increases intracellular calcium to enhance cardiac contractility (positive inotropy) while simultaneously augmenting vagal tone to slow conduction through the atrioventricular node

Digitalis glycosides, also referred to as cardiac glycosides, are a class of naturally derived cardiovascular agents—most notably digoxin—traditionally extracted from digitalis plants

They act primarily by reversibly inhibiting myocardial sodium-potassium adenosine triphosphatase (Na+/K+-ATPase), which increases intracellular calcium to enhance cardiac contractility (positive inotropy) while simultaneously augmenting vagal tone to slow conduction through the atrioventricular node Consequently, the class is used in clinical practice for the management of mild-to-moderate heart failure and for ventricular rate control in atrial fibrillation and other atrial tachyarrhythmias

Consequently, the class is used in clinical practice for the management of mild-to-moderate heart failure and for ventricular rate control in atrial fibrillation and other atrial tachyarrhythmias